Faculty

Manivel L Rengasamy, MD

Assistant Professor of Psychiatry

Contact Details

3811 O'Hara St.
Pittsburgh
 
PA
 
15213

Education & Training

MD
University of Texas Health Science Center at Houston
Child & Adolescent Psychiatry, UPMC Western Psychiatric Hospital
Child & Adolescent Psychiatry, UPMC Western Psychiatric Hospital
Child & Adolescent Mental Health Research, University of Pittsburgh School of Medicine

Research Interests

Child & adolescent psychiatry; Neural substrates of suicidality & depression; Cytokines & inflammation
Selected Research Publications & Products
  1. Hossein S, Rengasamy M, Uzamere A, Spotts C, Howland RH, Wallace ML, Mathew SJ, Price RB. Effects of ketamine on individual symptoms and symptom networks of depression in a randomised controlled trial of ketamine for treatment-resistant depression. Br J Psychiatry. 2025 May 13:1-10. doi: 10.1192/bjp.2024.276. Epub ahead of print. PMID: 40355133; PMCID: PMC12310196.
  2. Rengasamy M, Mathew S, Howland R, Griffo A, Panny B, Price R. Neural connectivity moderators and mechanisms of ketamine treatment among treatment-resistant depressed patients: a randomized controlled trial. EBioMedicine. 2024 Jan;99:104902. doi: 10.1016/j.ebiom.2023.104902. Epub 2023 Dec 22. PMID: 38141395; PMCID: PMC10788398.
  3. Rengasamy M, Price R. Replicable and robust cellular and biochemical blood marker signatures of depression and depressive symptoms. Psychiatry Research. 2024 Dec 1;342:116190.
  4. Rengasamy M, Moriarity D, Kraynak T, Tervo-Clemmens B & Price R. (2023). Exploring the multiverse: the impact of researchers analytic decisions on relationships between depression and inflammatory markers. Neuropsychopharmacology, 48(10), 1465-1474.
  5. Rengasamy M, Sylvester C, Shulman J & Pizon A. (2020). Contemporary characteristics and lethality correlates of serious suicide attempts in children and adolescents. Suicide and Life-Threatening Behavior, 50(3), 714-723.

Clinical Interests

Child & adolescent psychiatry
Selected Clinical Publications & Products
  1. Rengasamy M, Shalev A & Birmaher B. (2024). Psychopharmacology for Pediatric Depressive Disorders. In Pediatric Psychopharmacology Evidence: A Clinician's Guide (pp. 381-451). Cham: Springer Nature Switzerland.
  2. Rengasamy M & Birmaher B. Depressive Disorders. In Clinical manual of child and adolescent psychopharmacology. American Psychiatric Pub; 2023 Jul 28.
  3. Rengasamy M & Birmaher B. Bipolar II Disorder in Childhood and Adolescence. In Bipolar II Disorder: Recognition, Understanding, and Treatment. 2019 May 17 (pp. 241-262).

Education Interests

Selected Education Publications & Products
  1. Amin P, Esque J, Rengasamy M. Phone-Based Intervention for Suicidal Transition-Aged Adults, Poster presentation, UPMC Quality Improvement Fair. November 4, 2020.