Faculty

Finnegan J Calabro, PhD

Research Assistant Professor of Psychiatry and Bioengineering

Contact Details

3811 O'Hara St.
Pittsburgh
 
PA
 
15213
Email

Education & Training

PhD
Biomedical Engineering, Boston University
Psychiatry, University of Pittsburgh School of Medicine
Physical Medicine and Rehabilitation, University of Pittsburgh School of Medicine
Biomedical Engineering, Boston University

Professional Affiliations

Member, Society for Neuroscience
Member, Society for Developmental Cognitive Neuroscience

Research Interests

Cognitive & affective systems in adolescence; Adolescent multi-modal neuroimaging; Adolescent neurophysiological development
Selected Research Publications & Products
  1. Luna B, Tervo-Clemmens B, Calabro FJ. Considerations When Characterizing Adolescent Neurocognitive Development. Biol Psychiatry. 2020 May 11;doi: 10.1016/j.biopsych.2020.04.026 [Epub ahead of print]
  2. Tervo-Clemmens B, Quach A, Calabro FJ, Luna B. Adolescent Development ofInhibitory Control and Substance Use Vulnerability: A longitudinal neuroimaging study, Developmental Cognitive Neuroscience. (In press)
  3. Larsen B, Olafsson V, Calabro FJ, Laymon C, Tervo-Clemmens B, Campbell E, Minhas D, Montez D, Price J, Luna B. Maturation of the human striatal dopamine system revealed by PET and quantitative MRI, Nature Communications. 2020 Feb 12;11(1):846.
  4. Calabro FJ, Murty VP, Jalbrzikowski M, Tervo-Clemmens B, Luna B. Development of hippocampal prefrontal cortex interactions through adolescence. Cereb Cortex. 2019, Oct 31;bhz186. doi: 10.1093/cercor/bhz186. [Epub ahead of print]. PMID: 31670797.

Clinical Interests

Selected Clinical Publications & Products
  1. Valt C, Lopez-Caballero F, Tavella A, Altamura M, Bellomo A, Barrasso G, Coffman B, Iovine F, Rampino A, Saponaro A, Seebold D, Selvaggi P, Semisa D, Stolfa G, Bertolino A, Pergola G & Salisbury DF. (2024). Abnormal inter-hemispheric effective connectivity from left to right auditory regions during Mismatch Negativity (MMN) tasks in psychosis. Psychiatry Research, 342, 116189. https://doi.org/https://doi.org/10.1016/j.psychres.2024.116189

Pitt Psychiatry Research Published in Molecular Psychiatry

Collage of Molecular Psychiatry Co-Authors

Multiple Pitt Psychiatry investigators have recently published studies in Molecular Psychiatry. Below is a roundup of recent original research on adolescent neurodevelopment, aging and cognition, and the association between sleep and psychosis. Adolescent maturation of dorsolateral prefrontal cortex glutamate: GABA and cognitive function is supported by dopamine-related neurobiology Pitt Psychiatry investigators...

Nature Communications: A Canonical Trajectory of Executive Function Maturation from Adolescence to Adulthood

Luna and Colleagues Nature Communications 2023

Theories of human neurobehavioral development suggest executive functions mature from childhood through adolescence, a time when individuals may also experience peaks in risk-taking behaviors such as substance use, and increased vulnerability to psychiatric disorders. However, the timing of adolescent executive function development and the specific age when executive functions reach adult levels have been...

New Research on Brain Plasticity During Adolescence

Dr. Bea Luna

Postmortem studies of the prefrontal cortex have revealed changes in gamma-aminobutyric acid and glutamate across adolescence, which suggests shifts in excitation and inhibition balance consistent with critical period plasticity. However, questions have persisted regarding how gamma-aminobutyric acid and glutamate change through adolescence and how the balance of these inhibitory and excitatory neurotransmitters...

New Research on the Effects of Clozapine on Treatment-Resistant Schizophrenia

Dr. Deepak Sarpal

Deepak Sarpal, MD (Assistant Professor of Psychiatry), conducts research on the neurobiology of psychosis, focusing on schizophrenia. With a particular interest in treatment outcomes in psychotic disorders, Dr. Sarpal recently published two papers examining the effects of clozapine on treatment-resistant schizophrenia. Clozapine is an antipsychotic medication that exhibits superior efficacy for psychotic symptoms...

New Psychosis Research in Neuropsychopharmacology and Psychological Medicine

New Research in Psychological Medicine and Neuropsychopharmacology

More than 20 members of the Department of Psychiatry faculty conduct a wide range of research pertaining to schizophrenia, bipolar disorder, and other psychotic disorders. Recent Pitt Psychiatry studies in Neuropsychopharmacology and Psychological Medicine present new findings pertaining to clinical high risk for psychosis and first-episode psychosis. Reduced GABA/glutamate in the thalamus of individuals at...