David A Brent, MD

Distinguished Professor of Psychiatry, Pediatrics, Epidemiology, and Clinical and Translational Science and Endowed Chair in Suicide Studies

Contact Details

3811 O'Hara Street
Jamey Covaleski

Education & Training

Jefferson Medical College Medicine
University of Pittsburgh, Graduate School of Public Health Epidemiology
Western Psychiatric Institute and Clinic of UPMCGeneral Psychiatry and Child and Adolescent Psychiatry
University of Pennsylvania Cognitive Therapy InstituteCognitive Therapy
Western Psychiatric Institute & Clinic of UPMCPsychiatric Epidemiology

Selected Honors & Awards

Morselli Medal, International Academy of Suicide Research
Ruane Prize, National Alliance for Research on Schizophrenia and Affective Disorders
Top 10 Advancements and Breakthroughs in 2016, Brain & Behavior Research Foundation

Research Interests

Adolescent mood disorders and suicidal behavior; Bereavement, mental and physical health sequele; Clinical trials and therapeutics
Selected Research Publications & Products
  1. Brent DA, Perper JA, Goldstein CE, Kolko DJ, Allan MJ, Allman CJ, Zelenak JP. Risk factors for adolescent suicide. A comparison of adolescent suicide victims with suicidal inpatients. Arch GenPsychiatry. 1988;45:581-588.
  2. Brent D, Emslie G, Clarke G, Wagner KD, Asarnow JR, Keller M, Vitiello B, Ritz L, Iyengar S, Abebe K,Birmaher B, Ryan N, Kennard B, Hughes C, DeBar L, McCracken J, Strober M, Suddath R, Spirito A,Leonard H, Melhem N, Porta G, Onorato M, Zelazny J. Switching to another SSRI or to venlafaxinewith or without cognitive behavioral therapy for adolescents with SSRI-resistant depression: theTORDIA randomized controlled trial. JAMA. 2008;299:901-913.
  3. Brent DA, Melhem NM, Oquendo M, Burke A, Birmaher B, Stanley B, Biernesser C, Keilp J, Kolko D, Ellis S, Porta G, Zelazny J, Iyengar S, Mann JJ. Familial pathways to early-onsetsuicide attempt: a 5.6 year prospective study. JAMA Psychiatry. Feb 2015;72(2):160-168.
  4. Brent D, Melhem N, Donohoe MB, Walker M. The incidence and course of depression inbereaved youth 21 months after the loss of a parent to suicide, accident, or sudden natural death. Am J Psychiatry. 2009;166:786-794.
  5. Brent DA, Brunwasser SM, Hollon SD, Weersing VR, Clarke GN, Dickerson JF, Beardslee WR, Gladstone TR, Porta G, Lynch FL, Iyengar S, Garber J. Effect of a cognitive-behavioralprevention program on depression 6 years after implementation among at-riskadolescents: a randomized clinical trial. JAMA Psych. 2015;72(11):1110-1118.

Clinical Interests

Adolescent depression; Suicidal behavior; Mild traumatic brain injury
Selected Clinical Publications & Products
  1. Brent DA, Poling K. Cognitive Therapy Manual for Depressed and Suicidal Youth. Pittsburgh: University of Pittsburgh; 1997.
  2. Poling K, Brent DA, Birmaher B. Understanding and Coping with Bipolar Illness: A Survival Manual for Families. Pittsburgh: WPIC; 1998.
  3. Kerr MM, Brent DA, McKain B, McCommons PS. Postvention Standards Manual - A Guide for a School's Response in the Aftermath of a Sudden Death. Pittsburgh:University of Pittsburgh; 2010.
  4. Brent DA, Poling K, Goldstein TR. Treating Depressed and Suicidal Adolescents: A Clinician's Guide New York: Guilford Press; 2011.

Education Interests

Teaching about adolescent suicide & behavior; Supervision of child psychiatry residents; Mentoring medical students, residents & postdocs