David A Brent, MD
Education & Training
Selected Honors & Awards
- Brent DA, Perper JA, Goldstein CE, Kolko DJ, Allan MJ, Allman CJ, Zelenak JP. Risk factors for adolescent suicide. A comparison of adolescent suicide victims with suicidal inpatients. Arch GenPsychiatry. 1988;45:581-588.
- Brent D, Emslie G, Clarke G, Wagner KD, Asarnow JR, Keller M, Vitiello B, Ritz L, Iyengar S, Abebe K,Birmaher B, Ryan N, Kennard B, Hughes C, DeBar L, McCracken J, Strober M, Suddath R, Spirito A,Leonard H, Melhem N, Porta G, Onorato M, Zelazny J. Switching to another SSRI or to venlafaxinewith or without cognitive behavioral therapy for adolescents with SSRI-resistant depression: theTORDIA randomized controlled trial. JAMA. 2008;299:901-913.
- Brent DA, Melhem NM, Oquendo M, Burke A, Birmaher B, Stanley B, Biernesser C, Keilp J, Kolko D, Ellis S, Porta G, Zelazny J, Iyengar S, Mann JJ. Familial pathways to early-onsetsuicide attempt: a 5.6 year prospective study. JAMA Psychiatry. Feb 2015;72(2):160-168.
- Brent D, Melhem N, Donohoe MB, Walker M. The incidence and course of depression inbereaved youth 21 months after the loss of a parent to suicide, accident, or sudden natural death. Am J Psychiatry. 2009;166:786-794.
- Brent DA, Brunwasser SM, Hollon SD, Weersing VR, Clarke GN, Dickerson JF, Beardslee WR, Gladstone TR, Porta G, Lynch FL, Iyengar S, Garber J. Effect of a cognitive-behavioralprevention program on depression 6 years after implementation among at-riskadolescents: a randomized clinical trial. JAMA Psych. 2015;72(11):1110-1118.
- Brent DA, Poling K. Cognitive Therapy Manual for Depressed and Suicidal Youth. Pittsburgh: University of Pittsburgh; 1997.
- Poling K, Brent DA, Birmaher B. Understanding and Coping with Bipolar Illness: A Survival Manual for Families. Pittsburgh: WPIC; 1998.
- Kerr MM, Brent DA, McKain B, McCommons PS. Postvention Standards Manual - A Guide for a School's Response in the Aftermath of a Sudden Death. Pittsburgh:University of Pittsburgh; 2010.
- Brent DA, Poling K, Goldstein TR. Treating Depressed and Suicidal Adolescents: A Clinician's Guide New York: Guilford Press; 2011.
Now In JAMA Psychiatry: Severity and Variability of Depression in Predicting Suicide Attempt in High-Risk Individuals
The ability to predict suicidal behavior in psychiatric patients is one of the most challenging and high-stakes aspects of clinical practice. However, psychiatric diagnoses are of limited value for prediction because the risk for suicidal behavior can vary substantially over the course of a psychiatric illness. Researchers including University of Pittsburgh Department of Psychiatry investigators Nadine Melhem, PhD...
Brent and Colleagues Test New Smartphone-based Intervention to Reduce Suicide Attempts by Teens Following Hospital Discharge
Adolescent suicide and suicidal behavior have shown dramatic increases in the past decade, making suicide the second leading cause of death in this age group. The standard practice is to hospitalize adolescents at highest imminent risk for a suicide attempt, but the risk for suicidal behavior is highest within the first three weeks after discharge. Currently there are no interventions designed to decrease the risk...
In Longest and Most Detailed Study of Pediatric Grief Following Parental Loss to Date, Department Researchers Find Increased Rates of Depression and Functional Impairment
The death of parent is an incredibly stressful event for a child, and one that can have profound consequences for the child’s future wellbeing. However, little is known about the specific long-term impact of parental loss because these types of studies are challenging to conduct. Pitt Department of Psychiatry researchers recently completed a seven-year prospective examination of pediatric grief following parental...
New ETUDES Center Aims to Help PCPs Assess and Increase Engagement of Depressed and Suicidal Youth through Innovative New Technologies
Suicide is the second leading cause of death among adolescents and has increased by at least 20% in the past decade, but depressed and suicidal youth, who are at high risk for suicide, are often not identified, and when identified, often do not go for treatment. Pediatric primary care is an ideal place to identify youth at risk for suicide. At-risk youth are much more likely to present in primary care than in...