Michele A Bertocci, PhD
Education & Training
- Bertocci MA, Hanford L, Manelis A, Iyengar S, Youngstrom E, Gill MK, Monk K, Versace A, Bonar L, Bebko G, Ladouceur CD, Perlman SB, Diler R, Horwitz S, Arnold E, Hafeman D, Travis M, Kowatch R, Holland SK, Fristad M, Findling R, Birmaher B, Phillips ML. (in press) Clinical, cortical thickness, and neural activity predictors of future affective lability in youth at risk for bipolar disorder: initial discovery and independent sample replication. Molecular Psychiatry
- Soehner AM, Bertocci MA, Levenson JC, Goldstein TR, Diler R, Axelson D, Goldstein BI, Brent DA, Hickey MB, Monk K, Sakolsky D, Birmaher B, Phillips ML. Longitudinal associations between sleep patterns and psychiatric symptom severity in high-risk and community comparison youth. JAACAP, In Press
- Bertocci MA, Bebko G, Iyengar S, Dwojak A, Bonar L, Versace A, Forbes EE, Fournier J, Almeida JR, Perlman SB, Schirda C, Travis M, Gill MK, Diwadkar VA, Forbes E, Sunshine JL, Holland SK, Kowatch RA, Birmaher B, Axelson D, Horwitz SM, Frazier TW, Arnold LE, Fristad MA, Youngstrom EA, Findling RL, Phillips ML. (2017) Reward-Related Neural Activity Predicts Future Real-World Risky Substance Use Behaviors in Dysregulated Youth. Psychological Medicine 47(8):1357-69.
- Greenberg T, Bertocci MA, Chase HW, Fournier JC, Aslam H, Stiffler R, Lockovich J, Graur S, Bebko GM, Forbes EE, Phillips ML. (2017) Predicting quality of life from neural reactivity and anxiety a mediation model. Translational Psychiatry 7(7):e1178
- Bertocci MA, Bebko G, Dwojak A, Iyengar S, Ladouceur CD, Versace A, Fournier J, Bonar L, Almeida JR, Perlman SB, Schirda C, Travis M, Gill MK, Diwadkar VA, Forbes E, Sunshine JL, Holland SK, Kowatch RA, Birmaher B, Axelson D, Horwitz SM, Frazier TW, Arnold LE, Fristad MA, Youngstrom EA, Findling RL, Phillips ML. (2017) Longitudinal relationships among activity in neural circuitry underlying redirection of attention during emotional regulation and symptom severity in youth. Biological Psychiatry: CNNI 2(4):336-45.
Biological Psychiatry and Journal of Affective Disorders Research in Mood and/or Bipolar Disorders in Adolescence
New research from Pitt Psychiatry investigators provides insight into the development of anxiety, depression, and/or bipolar in adolescence. A Biological Psychiatry study examines the association between trauma exposure, reward neural circuitry function, and affective and anxiety disorders. In the Journal of Affective Disorders, investigators study whether child maltreatment and cognitive function influence the...
Now in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, Assessing Relationships Among Impulsive Sensation Seeking & Reward
Scientists seeking to improve understanding of bipolar disorder have focused on impulsive sensation seeking—a complex trait characterized by impulsivity (acting without advance thought) and sensation seeking (seeking new or extreme experiences). Some research has indicated that high impulsivity may be an early sign or symptom of bipolar disorder. Impulsive sensation seeking is associated with the greater valuation...
Study Is First to Show Impact of Transcranial Direct Current Stimulation on Reward and Affect in Bipolar Disorder
Bipolar disorder is a debilitating mental illness and the fourth leading cause of neurological disability worldwide. There is an urgent need for novel interventions that produce sustained alleviation of symptoms while not introducing challenging, long-term side effects. Previous studies have demonstrated abnormally elevated activity during reward expectancy in the left ventrolateral prefrontal cortex among...
Brain’s Reward Response Predicts Which Young Adults Seeking Mental Health Care Will Show Improvement Six Months Later, Finds Study by Eckstrand, Phillips and Colleagues
Young adulthood is an especially vulnerable time in development when symptoms of mental illness frequently arise. In fact, nearly one in five people between the ages of 18 and 25 seeks help for symptoms related to depression and anxiety. One particularly common and debilitating symptom is anhedonia, the inability to experience pleasure. A recent study by Pitt Department of Psychiatry researchers is the first to...