Melanie J Grubisha

Melanie J Grubisha, MD, PhD

Assistant Professor of Psychiatry

Contact Details

3811 O'Hara St.

Education & Training

University of Pittsburgh, School of Medicine Medicine
University of Pittsburgh, School of Medicine Molecular Pharmacology and Chemical Biology
UPMC Western Psychiatric HospitalPsychiatry
University of Pittsburgh School of MedicineTraining in Transformative Discovery in Psychiatry

Specialty Certifications

Board Certification
American Board of Psychiatry and Neurology

Research Interests

Dendritic deficits in schizophrenia
Selected Research Publications & Products
  1. Grubisha MJ, Sun X, MacDonald ML, Garver M, Sun Z, DeGiosio RA, Lewis DA, Yates NA, Camacho C, Ding Y, Sweet, RA. MAP2 is hyperphosphorylated in schizophrenia, altering its function. bioRxiv 683912; doi: https://doi.org/10.1101/683912
  2. Russell TA, Grubisha MJ, Remmers CL, Kang SK, Forrest MP, Smith KR, Kopeikina KJ, Gao R, Sweet RA, Penzes P. A schizophrenia-linked KALRN coding variant alters neuron morphology, protein function, and transcript stability. Biol Psychiatry. 2018 Mar 15;83(6):499-508. PMID:29241584 PMCID: PMC5809265
  3. Grubisha MJ, Lin CW, Tseng GC, Penzes P, Sibille E, Sweet RA. Age-Dependent Increase in Kalirin-9 and Kalirin-12 in Human Orbitofrontal Cortex. Eur J Neurosci. 2016 Oct;44(7):2483-2492. PMID: 27471199 PMCID: PMC5048532

Clinical Interests

Community psychiatry; Emergency psychiatric services

Education Interests

Medical student and resident education; Undergraduate research training