Ashley C Parr, PhD
Research Assistant Professor of Psychiatry
Contact Details
3811 O'Hara St.
Pittsburgh
PA
15213
Email parrac@upmc.edu
Education & Training
PhD
Neuroscience (Neuroeconomics), Queens University, Kingston, Ontario, Canada
Developmental Neuroscience, University of Pittsburgh School of Medicine
Professional Affiliations
Member, Society for Neuroscience
Member, Flux: The Society for Developmental Cognitive Neuroscience
Member, Organization for Human Brain Mapping
Member, Center for the Neural Basis of Cognition
Selected Honors & Awards
Young Investigator Award, Brain & Behavior Research Foundation
Research Interests
Developmental neuroscience; Dopamine development; Trajectories in health-risk behavior
Selected Research Publications & Products- Parr AC, Perica MI, Calabro F, Foran W, Moon CH, Hetherington H, Luna B. Adolescent maturation of prefrontal cortex glutamate: GABA and cognitive function is supported by dopamine-related neurobiology. Mol. Psychiatry. 2024 Dec 09. PMID: 39653761.
- Parr AC, Sydnor VJ, Calabro FC, Luna B. Adolescent-to-adult gains in cognitive flexibility are adaptively supported by reward processing, exploration, and neural variability. Invited Short Review. Curr. Opin. Behav. Sci. 2024 May 10; 58. PMID: 38826569.
- Tervo-Clemmens B, Calabro F, Parr AC, Fedor J, Foran W, Luna B. A canonical trajectory of executive function maturation during the transition from adolescence to adulthood. Nat. Commun. 2023 Oct 30; 14. PMID: 3793830.
- Parr AC, Calabro F, Tervo-Clemmens B, Larsen B, Foran W, Luna B. Contributions of dopamine-related basal ganglia neurophysiology to the developmental effects of incentives on inhibitory control. Dev. Cogn. Neurosci. 2022 Mar 17; 54. PMID: 35344773.
- Parr AC, Calabro F, Larsen B, Tervo-Clemmens B, Foran W, Olafsson V, Luna B. Dopamine-related striatal neurophysiology is associated with specialization of frontostriatal reward circuitry through adolescence. Prog. Neurobiol. 2021 Mar 02; 201. PMID: 33667595.
Clinical Interests
Selected Clinical Publications & Products- Calancie OG, Parr AC, Brien DC, Coe BC, Booij L, Khalid-Khan S, Munoz DP. Impairment of visual fixation and preparatory saccade control in borderline personality disorder with and without co-morbid attention-deficit hyperactivity disorder. Biol. Psychiatry. Cogn. Neurosci, Neuroimaging. 2024 Jul 18; 9(11): 1178-1187. PMID: 39032694.
- Cascone AD, Calabro F, Foran W, Larsen B, Nugiel T, Parr AC, Tervo-Clemmens B, Luna B, Cohen JR. Brain tissue iron neurophysiology and its relationship with the cognitive effects of dopaminergic modulation due to receipt of rewards or administration of methylphenidate in children with attention-deficit/hyperactivity disorder. Dev. Cogn. Neurosci. 2023 Jul 07; 63. PMID: 37453207.
- Parr AC, Riek H, Coe B, Pari G, Masellis M, Marras C, Munoz D. Genetic variation in the dopamine system is associated with mixed-strategy decision-making in patients with Parkinsons disease. Eur. J. Neurosci. 2022 Nov 30; 58(12):4523-4544. PMID: 36453013.
- Blazer A, Chengappa KNR, Foran W, Parr AC, Kahn DC, Luna B, Sarpal D. Changes in corticostriatal connectivity and striatal tissue iron associated with Clozapine efficacy in treatment-resistant schizophrenia. Psychopharmacology. 2022 Apr 18; 239(8): 2503-2514. PMID: 35435461.
- Parr AC, Calancie O, Coe B, Khan S, Munoz D. Impulsivity and emotional dysregulation predict choice behavior during a mixed-strategy game in adolescents with borderline personality disorder. Front. Neurosci.: Decision Neuroscience. 2022 Feb 13; 15. PMID: 35237117.
