Researchers on the Rise Lectures


VIP Treatment: Unique Effects of Alcohol on Prefrontal Cortex Disinhibitory Interneurons

Max Joffe, PhD Assistant Professor of Psychiatry, University of Pittsburgh School of Medicine

Epigenetic Regulation of Striatal Molecular Rhythm Alterations in Depression

Kyle Ketchesin, PhD Assistant Professor of Psychiatry, University of Pittsburgh School of Medicine

On February 17, 2023 our Researchers on the Rise series with feature presentations by two of our innovative early-career researchers: Max Joffe, PhD and Kyle Ketchesin, PhD.

Dr. Max JoffeDr. Joffe, Assistant Professor of Psychiatry, University of Pittsburgh School of Medicine, received a PhD and conducted NIMH-funded postdoctoral training in pharmacology at Vanderbilt University. His research concentrates on brain dysfunction and novel pharmacology in models of alcohol use disorder. Dr. Joffe currently leads a National Institute on Alcohol Abuse and Alcoholism R00 Award designed to test the hypothesis that sex differences in drinking are modulated by mGlu receptors on specific neuronal subpopulations in the prefrontal cortex. 

Dr. Kyle KetchesinDr. Ketchesin is an Assistant Professor of Psychiatry at the University of Pittsburgh School of Medicine. He received his PhD in neuroscience from the University of Michigan. Upon earning his doctorate, Dr. Ketchesin joined the Pitt Department of Psychiatry as a postdoctoral fellow in the National Institute of Mental Health (NIMH)-funded Training for Transformative Discovery in Psychiatry T32 training program under the mentorship of Colleen McClung, PhD (Professor of Psychiatry and Clinical and Translational Science). Dr. Ketchesin investigates the epigenetic mechanisms underlying circadian dysfunctions in mood disorders, particularly depression. He is principal investigator of an NIMH K01 career development award focused on the role of DNA methylation in regulating striatal molecular rhythm alterations in depression. 

Lectures will be offered as a hybrid event. Join us in-person in the UPMC Western Psychiatric Hospital Auditorium (masking is required) or to attend remotely, use the Zoom information below to join us:

Zoom Link:
Meeting ID: 927 5532 8509  

For More Information. Please contact Jeanie Knox at  

CONTINUING EDUCATION CREDITS. The entirety of this program will be a lecture by the speaker(s). All individuals able to control the content of this educational activity are required to disclose all relevant financial relationships with any proprietary entity producing, marketing, re-selling, or distributing health care goods or services, used on, or consumed by, patients. Registration is not required for this event. This event is free and there will be no refunds. The University of Pittsburgh is an affirmative action, equal opportunity institution. The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The University of Pittsburgh School of Medicine designates this educational activity for a maximum of 1.5 AMA PRA Category 1 CreditsTM. Each physician should only claim credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded .15 continuing education units (CEUs), which are equal to 1.5 contact hours. In accordance with Accreditation Council for Continuing Medical Education requirements on disclosure, information about relationships of presenters with commercial interests (if any) will be included in materials which will be distributed at the time of the conference. WPH is approved by the American Psychological Association to offer continuing education for psychologists. WPH maintains responsibility for this program and its contents. This program is being offered for 1.5 continuing education credits. The indicated number of clock hours of continuing education is provided through UPMC Western Psychiatric Hospital’s Office of Educational Resources and Planning, a PA-approved provider of social work continuing education in accordance with all the applicable educational and professional standards of the Pennsylvania State Board of Social Workers, Marriage and Family Therapist. These clock hours satisfy requirements for LSW/LCSW, LPC and LMFT renewal. For more information, call (412) 204-9085.