Education & Training
Selected Honors & Awards
- Liu Z, Wang Y, Cai Li, Li Yizhi, Chen B, Dong Y, Huang YH (2016) Prefrontal cortex to accumbens projections in sleep regulation of reward. J Neurosci 36: 7897-7910 *Featured article.
- Chen B, Wang Y, Liu X, Liu Z, Dong Y, Huang YH (2015) Sleep regulates incubation of cocaine craving. J Neurosci 35: 13300-13310. *Featured article.
- Ma YY, Lee BR, Wang X, Guo C, Liu L, Cui R, Lan Y, Balcita-Pedicino JJ, Wolf ME, Sesack SR, Shaham Y, Schlter OM, Huang YH, Dong Y (2014) Bi-directional modulation of incubation of cocaine craving by silent synapse-based remodeling of prefrontal cortex to accumbens projections. Neuron 83:1453-1467.
- Lee BR, Ma YY, Huang YH, Wang X, Otaka M, Ishikawa M, Neumann PA, Graziane NM, Brown TE, Suska A, Guo C, Lobo MK, Sesack SR, Wolf ME, Nestler EJ, Shaham Y, Schlter OM, Dong Y (2013) Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving. Nat Neurosci 16:1644-1651.
- Huang YH, Lin Y, Mu P, Lee BR, Brown TE, Wayman G, Marie H, Liu W, Yan Z, Sorg BA, Schlter OM, Zukin RA, Dong Y (2009) In vivo cocaine experience generates silent synapses. Neuron 63:40-47.
Pitt Psychiatry Awarded $14.8M National Institute on Drug Abuse Center Grant Focused on the Role of Sleep and Circadian Rhythms in Substance Abuse
The National Institute on Drug Abuse (NIDA) has awarded Pitt Psychiatry a Center of Excellence (P50) grant to fund the Center for Adolescent Reward, Rhythms and Sleep (CARRS). The CARRS Center will be led by Colleen McClung, PhD (Professor of Psychiatry and Clinical and Translational Science) and Daniel Buysse, MD (UPMC Professor of Sleep Medicine and Professor of Psychiatry and Clinical and Translational Science)...
Now in Biological Psychiatry: Dissecting the Neural Circuity Underlying Sleep-Mediated Regulation of Reward
Regular sleep is critical for both health and optimal brain functioning. Sleep deprivation affects several regions within the brain’s reward circuitry, including the nucleus accumbens, the reward processing hub, as well as connected regions such as the amygdala. Changes in these brain regions are involved in impulsivity and increased drive for rewarding stimuli (such as sweet food), common symptoms of sleep...
University of Pittsburgh Awards Tenure to Yanhua Huang, PhD
We are delighted to announce that Yanhua Huang, PhD, has been appointed Tenured Associate Professor of Psychiatry by the University of Pittsburgh. Dr. Huang’s research focuses on the role of changes in sleep on neural plasticity in reward circuits, with a focus on the association between sleep loss and addiction. She is currently the PI of five federally funded grants, including a National Institute on Drug Abuse...
Now in The Journal of Neuroscience: Calcineurin Infusions to the Lateral Amygdala Reduce the Reinstatement of Cocaine-Cue Memories
Treatment for substance use disorders, devastating and pervasive illnesses, are complicated by a high propensity for relapse. Relapse can occur when an individual encounters a familiar stimulus that has, in the past, induced cravings. One strategy for potentially preventing relapse is to weaken these maladaptive memories. Two approaches for doing so include interfering with memory reconsolidation—disrupting the...