Pamela Lukasewicz Ferreira, PhD
Research Assistant Professor of Psychiatry
Contact Details
3811 O'Hara St.
Pittsburgh
PA
15213
Education & Training
PhD
Pharmaceutical Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Brazil
Psychiatry, University of Pittsburgh School of Medicine
Professional Affiliations
Member, ISTAART, Alzheimer's Association
Research Interests
Alzheimer's disease and related dementias; Neuroimaging biomarkers; Fluid biomarkers in clinical trials
Selected Research Publications & Products- Borelli WV, Ferreira PCL, Brum WS, Ferrari-Souza JP, Carello-Collar G, Holz M, Tizeli V, Strelow MZ, Formoso C, Fagundes Chaves ML, Rocha A, Aguzzoli CS, Rohden F, Souza DG, Schumacher Schuh AF, Povala G, Bellaver B, Rosa-Neto P, Castilhos RM, Pascoal TA & Zimmer ER. (2025). Diagnostic performance of Alzheimers disease blood biomarkers in a Brazilian cohort. medRxiv: 2025.2002.2023.24319116.
- Rohden F, Ferreira PCL, Bellaver B, Ferrari-Souza JP, Aguzzoli CS, Soares C, Abbas S, Zalzale H, Povala G, Lussier FZ, Leffa DT, Bauer-Negrini G, Rahmouni N, Tissot C, Therriault J, Servaes S, Stevenson J, Benedet AL, Ashton NJ, Karikari TK, Tudorascu DL, Zetterberg H, Blennow K, Zimmer ER, Souza D, Rosa-Neto P & Pascoal TA (2025). Glial reactivity correlates with synaptic dysfunction across aging and Alzheimers disease. Nature Communications 16(1): 5653.
- Abbas S, Ferreira PCL, Bellaver B, Povala G, Rohden F, Aguzzoli CS, Zalzale H, Ferrari-Souza JP, Leffa DT, Lussier FZ, Soares C, Bauer-Negrini G, Oliveira-Junior MS, Rodrigues MS, Saha P, Ruppert E, Medeiros MS, Tissot C, Therriault J, Rahmouni N, Servaes S, Benedet AL, Ashton NJ, Tudorascu DL, Gauthier S, Karim H, Hong CH, Roh HW, Zimmer ER, Karikari TK, Zetterberg H, Blennow K, Saeed A, Son SJ, Rosa-Neto P & Pascoal T (2025). Utility of plasma GFAP as a secondary endpoint for clinical trials in Alzheimers disease. The Journal of Prevention of Alzheimer's Disease 12(7): 100205
- Ferreira PCL, Ferrari-Souza JP, Tissot C, Bellaver B, Leffa DT, Lussier F, Povala G, Therriault J, Benedet AL, Ashton NJ, Cohen AD, Lopez OL, Tudorascu DL, Klunk WE, Soucy JP, Gauthier S, Villemagne V, Zetterberg H, Blennow K, Rosa-Neto P, Zimmer ER, Karikari TK, & Pascoal TA for the Alzheimer's Disease Neuroimaging Initiative. Potential utility of plasma p-tau and neurofilament light chain as surrogate biomarkers for preventive clinical trials. Neurology. 2023 Jul 4;101(1):38-45. doi: 10.1212/WNL.0000000000207115. Epub 2023 Mar 6. PMID: 36878697; PMCID: PMC10351303.
- Ferreira PCL, Therriault J, Tissot C, Ferrari-Souza JP, Benedet AL, Bellaver B, Povala G, Leffa DT, Brum WS, Lussier FZ, Bezgin G, Servaes S, Vermeiren MV, Macedo A, Cabrera A, Kang MS, Tudorascu DL, Klunk WE, Villemagne VL, Cohen AD, Zimmer ER, Karikari TK, Ashton NJ, Zetterberg H, Blennow K, Gauthier S, Rosa-Neto P, Pascoal TA. (2023). Plasma p-tau231 and p-tau217 inform predominantly on tau tangles accumulation in cognitively impaired individuals. Alzheimer & Dementia. 112. doi: 10.1002/alz.13393
