Faculty

Deepak K Sarpal, MD

Assistant Professor of Psychiatry

Contact Details

3501 Forbes Avenue
Pittsburgh
 
PA
 
15213
Phone 412-246-5618
Email

Education & Training

MD
St. George's University School of Medicine
Psychiatry, Zucker Hillside Hospital, Hofstra Northwell School of Medicine

Specialty Certifications

Board Certification
American Board of Psychiatry and Neurology

Selected Honors & Awards

Rising Star Award, Pittsburgh Foundation

Research Interests

Treatment outcomes; trajectories; Psychiatric neuroimaging; Therapeutic trials
Selected Research Publications & Products
  1. Sarpal DK, Robinson DG, Fales C, Lencz T, Argyelan M, Karlsgodt KH, Gallego JA, John M, Kane JM, Szeszko PR, Malhotra AK (2017). Relationship between Duration of Untreated Psychosis and Intrinsic Corticostriatal Connectivity in Patients with Early Phase Schizophrenia. Neuropsychopharmacology. Apr 5. doi: 10.1038/npp.2017.55.
  2. Sarpal DK, Argyelan M, Robinson DG, Szeszko PR, Karlsgodt KH, John M, Weissman N, GallegoJA, Kane JM, Lencz T, Malhotra AK (2016). Baseline Striatal Functional, Connectivity as aPredictor of Response to Antipsychotic Drug Treatment. The American Journal of Psychiatry 173; 69- 77.
  3. Sarpal DK, Robinson D, Lencz T, Argyelan M, Ikuta T, Karlsgodt K, Gallego JA, KaneJM, Szeszko PR, Malhotra AK (2015). Antipsychotic Treatment and Functional Connectivity of the Striatum in First-Episode Schizophrenia. JAMA Psychiatry 72: 5.
  4. Eisenberg D, Sarpal D, Kohn PD, Meyer-Lindenberg A, Apud J, Wint D, Kolachana B, Weinberger DR, Berman KF (2010). Catechol-O-methyltransferase Val158Met Genotype and Resting Regional Cerebral Blood Flow in Medication-Free Patients with Schizophrenia. Biological Psychiatry 67:287-290.
  5. Sarpal D, Buchsbaum BR, Kohn PD, Kippenhan JS, Mervis CB, Morris CA, Meyer Lindenberg A, Berman KF (2008). A genetic model for understanding higher-ordervisual processing: functional interactions of the ventral visual stream in Williams syndrome. Cerebral Cortex 18: 2402-2409.

Clinical Interests

Psychotic disorders; Psychiatric phenomenology; Integrating psychopharmacology/psychotherapy

Education Interests

Treatment outcomes; trajectories; Psychiatric neuroimaging; Therapeutic trials

New Research on the Effects of Clozapine on Treatment-Resistant Schizophrenia

Dr. Deepak Sarpal

Deepak Sarpal, MD (Assistant Professor of Psychiatry), conducts research on the neurobiology of psychosis, focusing on schizophrenia. With a particular interest in treatment outcomes in psychotic disorders, Dr. Sarpal recently published two papers examining the effects of clozapine on treatment-resistant schizophrenia. Clozapine is an antipsychotic medication that exhibits superior efficacy for psychotic symptoms...

Recent Clinical Innovations in Consultation-Liaison Psychiatry and Telepsychiatry 

Recent Clinical Innovations from Pitt Psychiatry 

Recent papers from the Department of Psychiatry examine clinical initiatives around consultation-liaison psychiatry and first-episode psychosis, consultation-liaison psychiatry in the obstetrical setting, and the expansion of telepsychiatry during the COVID-19 pandemic. Journal of the Academy of Consultation-Liaison Psychiatry: First-Episode Psychosis and the Role of the Psychiatric Consultant Timely recognition...

New Psychosis Research in Neuropsychopharmacology and Psychological Medicine

New Research in Psychological Medicine and Neuropsychopharmacology

More than 20 members of the Department of Psychiatry faculty conduct a wide range of research pertaining to schizophrenia, bipolar disorder, and other psychotic disorders. Recent Pitt Psychiatry studies in Neuropsychopharmacology and Psychological Medicine present new findings pertaining to clinical high risk for psychosis and first-episode psychosis. Reduced GABA/glutamate in the thalamus of individuals at...

Research in First Episode and Clinical High Risk Psychosis

A Look at What’s Happening in Psychosis Research at Pitt Psychiatry

EPINET: First-Episode Psychosis Research The UPMC Western Psychiatric Hospital (WPH) Services for the Treatment of Early Psychosis (STEP) clinic is an outpatient program for the evaluation, treatment, and rehabilitation of people who may be experiencing early signs of a psychotic illness. STEP is one of 20 clinics across Maryland and Pennsylvania that will be included in an Early Psychosis Intervention Network...