Publications

Developing a Clinician Educator Faculty Development Program: Lessons LearnedFertig, AM, Tew JD, Douaihy AB, Nash KC, Solai LKK, Travis MJ, Zippay LB, Matthews KA and Lewis DAAcademic Psychiatry, 2017 Jun;41(3):417-422Over the past 25 years, the roles of physicians as clinicians, educators, and administrators in academic medicine have received increasing attention. Awareness of the complex nature of this career path...

Pathological Basis for Deficient Excitatory Drive to Cortical Parvalbumin Interneurons in SchizophreniaChung DW, Fish KN and Lewis DAAmerican Journal of Psychiatry, 2016 Nov 1;173(11):1131-1139.Deficient excitatory drive to parvalbumin-containing cortical interneurons is proposed as a key neural substrate for altered gamma oscillations and cognitive dysfunction in schizophrenia. However, a pathological entity...

Prefrontal Cortex to Accumbens Projections in Sleep Regulation of RewardLiu Z, Wang Y, Cai L, Li Y, Chen B, Dong Y, and Huang YHJournal of Neuroscience, Published online, 2016Sleep profoundly affects the emotional and motivational state. In humans and animals, loss of sleep often results in enhanced motivation for reward, which has direct implications for health risks as well as potential benefits. Dr. Yanhua Huang...

Parsing Heterogeneity in the Brain Connectivity of Depressed and Healthy Adults during Positive MoodPrice RB, Lane S, Gates K, Kraynak TE, Horner MS, Thase ME and Siegle GJBiological Psychiatry, Published online, 2016Psychiatric diagnoses exhibit significant heterogeneity in symptom presentation. Major depression, for example, has 16,400 possible combinations of symptoms contained within the nine DSM-5 criteria...

Altered expression of ARP2/3 complex signaling pathway genes in prefrontal layer 3 pyramidal cells in schizophreniaDatta D, Arion D, Roman KM, Volk DW and Lewis DAAmerican Journal of Psychiatry, Published online August 2016Lower dendritic spine density on layer 3 pyramidal cells in the dorsolateral prefrontal cortex (DLPFC) appears to contribute to cognitive dysfunction in schizophrenia, whereas psychosis is...

Neurometabolic disorders: Potentially treatable abnormalities in patients with treatment-refractory depression and suicidal behaviorPan LA, Martin P, Zimmer T, Segreti AM, Kassiff S, McKain BW, Baca CA, Rengasamy M, Hyland K, Walano N, Steinfeld R, Hughes M, Dobrowolski SK, Pasquino M, Diler D, Perel J, Finegold DN, Peters DG, Naviaux RK, Brent DA and Vockley J.American Journal of Psychiatry, 2017, 174(1):42...