Marta Peciña, MD, PhD

Associate Professor of Psychiatry and Bioengineering

Areas of Expertise

  • Mood Disorders
  • Anxiety, OCD & Trauma Disorders
  • Basic & Translational Neuroscience
  • AI & Computational Methods
  • Neuromodulation
Marta Peciña, MD, PhD
Expertise & Interests Selected Publications Education & Credentials Related News

Expertise & Interests

Research Interests

Neuroimaging predictors of treatment response; Interactions between belief, learning & mood; Computational models of placebo effects

Clinical Interests

Depression; Neuroimaging; Neuromodulation

Education Interests

Research mentorship; Resident education; Career development

Selected Publications

  1. Handoko K, Neppach A, Snyder I, Karim HT, Dombrovski AY, Pecina M. Expectancy-mood neural dynamics predict mechanisms of short- and long-term antidepressant placebo effects. Biol Psychiatry Cogn Neurosci Neuroimaging. 2025 Aug;10(8):794-803. doi: 10.1016/j.bpsc.2025.01.002. Epub 2025 Jan 11.
  2. Pecina M, Chen J, Karp JF, Dombrovski AY. Dynamic feedback between antidepressant placebo expectancies and mood are encoded in the dorsal attention and salience networks. JAMA Psychiatry, 2023 Apr 1;80(4):389-398. PMID: 36857039, PMCID: PMC9979016.
  3. Pecina M, Chen J, Lyew T, Karp JF, Dombrovski AY. Opioid antagonist naltrexone partially abolishes the antidepressant placebo effect and reduces OFC encoding of reinforcement. Biol Psychiatry Cogn Neurosci Neuroimaging. 2021 Mar 6;S2451-9022(21)00055-0. doi: 10.1016/j.bpsc.2021.02.009.
  4. Chen J, Mizuno A, Lyew T, Karim H, Karp JF, Dombrovski AY, Pecina M. Naltrexone modulates contextual processing in depression. Neuropsychopharmacol. (2020). https://doi.org/10.1038/s41386-020-00809-2.
  5. Pecina M, Dombrovski AY, Price R, Karim H. Neurocomputational mechanisms of antidepressant placebo effects. J Psychiatry Brain Sci. 2021;6: Published online 2021 Feb 15. doi: 10.20900/jpbs.20210001. PubMed Central PMCID: PMC7963355.

Education & Credentials

Education & Training

Education
MD, University of Navarre, School of Medicine
Education
PhD, Neuroscience, University of Navarre, School of Medicine
Residency
Psychiatry, University of Navarre Medical Center
Postdoctoral
Neuroimaging, University of Michigan

Professional Affiliations

  • Member, Society of Biological Psychiatry
  • Member, Society of Interdisciplinary Placebo Studies
  • Member, American College of Neuropsychopharmacology

Selected Honors & Awards

  • Young Physician Scientist Award, American Society of Clinical Investigation
  • Rising Star Award, Pittsburgh Foundation
  • New Investigator Award, International Society for CNS Clinical Trials and Methodology

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