Participate in Research

People like you make the difference!

By participating in a research project, you play a part in helping physicians and researchers develop better ways to diagnose and treat people with mental illness. As a research participant, you learn about the causes of specific mental health problems and what can be done to manage these conditions. 

Find a study to participate in: Enter a keyword below (for example, "depression")

OR

Select keyword(s) from the list below:

Project Title:
Mood and Brain Circuitry in Adolescents (MBA) Study
Principal Investigator:
Cecile Ladouceur, PhD
For Information Contact:
Allison Brown (Telephone: 412-624-8121; Email: MBAstudy@pitt.edu)
What We Are Studying:
The purpose of this study is to help researchers examine how patterns of brain-behavior relationships involved in processing positive emotional and rewarding information are associated with mood symptoms in adolescents with depression. The researchers hope that the data collected from this study will help them identify more personalized interventions for depression, especially in those with more varying mood symptoms. This study does not involve any treatments or medications.
Who Is Eligible to Participate:
Individuals who are: Ages 12-17 years old; Currently depressed; Not currently taking any medication to treat depression, and; Have no non-removable metal in their bodies (dental fillings are OK)
Who Is Not Eligible to Participate:
Those unable to undergo fMRI scanning. Those who have a have a lifetime history of psychotic, autistic, or bipolar disorders.
What Participation Involves:
Participation involves an in-person visit to the CAND Lab on the University of Pittsburgh campus which will take approximately 3 hours to complete. This visit will include completing interviews and questionnaires. A second in-person visit to the Magnetic Resonance Research Center located within UPMC Presbyterian for a fMRI scan. This visit will take about 2 hours to complete. Over the next 2 years, visits will be repeated every 6 months. Participants can choose between coming into the lab for the visit or having the research team come to their home.
Do Participants Receive Compensation as Part of the Study:
Yes
What Compensation Do Participants Receive:
Compensation is provided. Please contact the study coordinator for more details.
Brochure Location:
Project Title:
EASE: Emotional Awareness and Skills Enhancement Study for ASD
Principal Investigator:
Carla Mazefsky, PhD
For Information Contact:
Please contact the study coordinator (Email: autismrecruiter@upmc.edu; Toll free-1866-647-3436)
What We Are Studying:
The Center for Excellence in Autism Research at the University of Pittsburgh is conducting a research study to evaluate a new treatment for adolescents and young adults with autism spectrum disorders (ASD) who struggle with handling their emotions.
Who Is Eligible to Participate:
Verbal individuals with ASD ages 12-21 years old with an IQ> 80 who have difficulties with regulating their emotions.
Who Is Not Eligible to Participate:
Individuals with a diagnosis of a psychotic disorder and/or current concerns of suicidality are not eligible to participate.
What Participation Involves:
Participants will be randomized to either EASE Therapy or Supportive Therapy. Each therapy involves 16 weekly sessions. Assessments will occur before treatment (baseline),at the mid-point and at the end of treatment, and three months after treatment. Assessments will include parent, other reporter and self-report questionnaires via an online secure system as well as some direct assessment. Participants will also be invited to participate in an optional part of the study designed to help us understand how the brain responds to emotions and mindfulness. This will involve playing a game at a computer while wearing a cap which has sensors in it and cables attached to it that measures brain activity called Electroencephalography (EEG).
Do Participants Receive Compensation as Part of the Study:
Yes
What Compensation Do Participants Receive:
Compensation for completing the study assessments and reimbursement for parking or public transportation.
Brochure Location:
Project Title:
Progressive Early Psychosis Pathology
Principal Investigator:
Dean Salisbury, PhD
For Information Contact:
Contact the Clinical Neurophysiology Research Lab; 412-246-6533; cnrlras.upmc@gmail.com
What We Are Studying:
This study examines psychosis and brain activity relating attention and sound.
Who Is Eligible to Participate:
Healthy controls, those at risk for developing psychosis, and people experiencing their first episode of psychosis
Who Is Not Eligible to Participate:
General (regardless of group): a) DSM intellectual developmental disorder (IQ of 70 or lower); b) significant head injury; c) medical illness affecting brain structure or function; d) significant neurologic disorder (e.g seizure disorder); e) inability to provide informed consent; f) hearing problems (defined as >15dB nHL hearing difference between left and right ears at any frequency, or inability to hear tones at 30dB nHL or lower at any frequency); g) inability to fit in scanning equipment (MEG: larger than 300lbs, taller than 6'4", head circumference greater than 62cm. MRI greater than 300lbs); h) metal in body deemed not safe for the MRI or that may interfere with the MEG. i) concussion with loss of consciousness (LOC) greater than 10 minutes; j) history of electroconvulsive therapy or electroshock treatments (ECT); k) diabetes with associated seizures, loss of sensation/weakness in arms or legs, or momentary LOC and; l) pregnancy, as determined by self-report.
What Participation Involves:
Participants will take part in combined MEG/EEG and MRI testing and clinical evaluations at 1 or 4 separate time points over the course of a year.
Do Participants Receive Compensation as Part of the Study:
Yes
What Compensation Do Participants Receive:
Compensation is provided. Please contact the lab for more details.
Brochure Location:
Project Title:
Depression Treatment Study
Principal Investigator:
Rebecca Price, PhD
For Information Contact:
Michelle Degutis, canlab@pitt.edu, 412-648-6554
What We Are Studying:
Testing an intravenous infusion of ketamine as a novel, multi-component treatment for depression
Who Is Eligible to Participate:
Adults ages 18-60 who are feeling down, low, or depressed and have tried at least one standard antidepressant medication during the current period of depression, without complete success.
Who Is Not Eligible to Participate:
Adults diagnosed with bipolar disease; those unable to safely complete an MRI assessment
What Participation Involves:
Participants will receive an intravenous infusion of ketamine and complete sessions of a computer-based intervention designed to "retrain the brain," or receive placebo treatments; complete clinical interviews, questionnaires, fMRI brains scans and computer-based tasks."
Do Participants Receive Compensation as Part of the Study:
Yes
What Compensation Do Participants Receive:
Participants will be compensated up to $450 for completing the study.
Brochure Location:
Project Title:
Compulsive Behavior Study
Principal Investigator:
Rebecca Price, PhD
For Information Contact:
Marlee Pyzewski, canlab@pitt.edu, 412-864-3515
What We Are Studying:
The study examines the brain mechanisms involved in overcoming compulsive behaviors.
Who Is Eligible to Participate:
Adults ages 18-55, who feel compelled to complete repetitive, unwanted behaviors aimed at reducing distress or obtaining absolute certainty.
Who Is Not Eligible to Participate:
Those unable to safely complete an MRI assessment
What Participation Involves:
Clinical interviews, questionnaires, fMRI brain scan, computer-based behavioral tasks (including repeated administration of a safe, mild electric shock), and non-invasive brain stimulation (Transcranial Magnetic Stimulation) designed to stimulate specific brain regions.
Do Participants Receive Compensation as Part of the Study:
Yes
What Compensation Do Participants Receive:
Participants will receive up to $260 for completing the study.
Brochure Location:
Project Title:
Sleep, Circadian Rhythms and Cardiometabolic Risk in Retired Shift Worker
Principal Investigator:
Daniel Buysse, MD
For Information Contact:
Michael Lightfoot, lightfootm@upmc.edu, WPIC E-1136, 3811 O'Hara Street, 15213, 412-246-6419; or Sarah Kimutis, kimutiss@upmc.edu, 412-246-6643.
What We Are Studying:
This study examines the effects of night shift work exposure on heart health, sleep and emotional expression into retirement.
Who Is Eligible to Participate:
Individuals aged >60 years old who have been retired at least 1 year and are medically stable, and have a history of night shift work or a history of daylight work (with little or no night shift work).
Who Is Not Eligible to Participate:
Individuals who are medically or emotionally unstable, or who are insulin dependent diabetics, in current treatment for sleep apnea, using of beta blockers, or using tobacco.
What Participation Involves:
Participants will complete an initial evaluation, medical history and exam, cardiovascular assessment, blood samples, computer assessments. Some participants will completed a 2 1/2 day (60 hour) sleep lab study
Do Participants Receive Compensation as Part of the Study:
Yes
What Compensation Do Participants Receive:
Participants will be compensated up to $450. Please contact the project coordinators for details.
Brochure Location: