David A Brent, MD
Education & Training
Selected Honors & Awards
- Brent DA, Perper JA, Goldstein CE, Kolko DJ, Allan MJ, Allman CJ, Zelenak JP. Risk factors for adolescent suicide. A comparison of adolescent suicide victims with suicidal inpatients. Arch GenPsychiatry. 1988;45:581-588.
- Brent D, Emslie G, Clarke G, Wagner KD, Asarnow JR, Keller M, Vitiello B, Ritz L, Iyengar S, Abebe K,Birmaher B, Ryan N, Kennard B, Hughes C, DeBar L, McCracken J, Strober M, Suddath R, Spirito A,Leonard H, Melhem N, Porta G, Onorato M, Zelazny J. Switching to another SSRI or to venlafaxinewith or without cognitive behavioral therapy for adolescents with SSRI-resistant depression: theTORDIA randomized controlled trial. JAMA. 2008;299:901-913.
- Brent DA, Melhem NM, Oquendo M, Burke A, Birmaher B, Stanley B, Biernesser C, Keilp J, Kolko D, Ellis S, Porta G, Zelazny J, Iyengar S, Mann JJ. Familial pathways to early-onsetsuicide attempt: a 5.6 year prospective study. JAMA Psychiatry. Feb 2015;72(2):160-168.
- Brent D, Melhem N, Donohoe MB, Walker M. The incidence and course of depression inbereaved youth 21 months after the loss of a parent to suicide, accident, or sudden natural death. Am J Psychiatry. 2009;166:786-794.
- Brent DA, Brunwasser SM, Hollon SD, Weersing VR, Clarke GN, Dickerson JF, Beardslee WR, Gladstone TR, Porta G, Lynch FL, Iyengar S, Garber J. Effect of a cognitive-behavioralprevention program on depression 6 years after implementation among at-riskadolescents: a randomized clinical trial. JAMA Psych. 2015;72(11):1110-1118.
- Brent DA, Poling K. Cognitive Therapy Manual for Depressed and Suicidal Youth. Pittsburgh: University of Pittsburgh; 1997.
- Poling K, Brent DA, Birmaher B. Understanding and Coping with Bipolar Illness: A Survival Manual for Families. Pittsburgh: WPIC; 1998.
- Kerr MM, Brent DA, McKain B, McCommons PS. Postvention Standards Manual - A Guide for a School's Response in the Aftermath of a Sudden Death. Pittsburgh:University of Pittsburgh; 2010.
- Brent DA, Poling K, Goldstein TR. Treating Depressed and Suicidal Adolescents: A Clinician's Guide New York: Guilford Press; 2011.
Now in JAMA Psychiatry: The “Twin Epidemics” of Increasing Parental Use of Opioids and Rate of Youth Suicide
As opioid use has risen nationwide during the last 15 years, a concurrent epidemic of increased youth suicide has also occurred during this period. Researchers have explored the potential of several cultural factors to explain the increase in the suicide rate of children and adolescents, including a warning from the Food and Drug Administration about the use of antidepressants and potential suicidal ideation, the...
New Research in the Journal of the American Academy of Child & Adolescent Psychiatry Examines Family Functioning in Offspring of Bipolar Parents
For people living with bipolar disorder, challenging family relations can both result from and aggravate the disorder’s symptoms. Existing studies that examine the family environment of young people with familial risk for bipolar disorder have not distinguished whether stressors—such as high rates of conflict—are uniquely related to this disorder or are similarly experienced by families affected by other, non...
Now In JAMA Psychiatry: Severity and Variability of Depression in Predicting Suicide Attempt in High-Risk Individuals
The ability to predict suicidal behavior in psychiatric patients is one of the most challenging and high-stakes aspects of clinical practice. However, psychiatric diagnoses are of limited value for prediction because the risk for suicidal behavior can vary substantially over the course of a psychiatric illness. Researchers including University of Pittsburgh Department of Psychiatry investigators Nadine Melhem, PhD...
Brent and Colleagues Test New Smartphone-based Intervention to Reduce Suicide Attempts by Teens Following Hospital Discharge
Adolescent suicide and suicidal behavior have shown dramatic increases in the past decade, making suicide the second leading cause of death in this age group. The standard practice is to hospitalize adolescents at highest imminent risk for a suicide attempt, but the risk for suicidal behavior is highest within the first three weeks after discharge. Currently there are no interventions designed to decrease the risk...