Education & Training
Selected Honors & Awards
- Parekh, P.K., Becker-Krail, D., Sundaravelu, P., Ishigaki, S., Okado, H., Sobue, G., Huang, Y., and McClung, C.A. (2017) Altered GluA1 function and accumbal synaptic plasticity in the Clockdelta19 model of bipolar mania. Biological Psychiatry, in press
- Chen, C.Y., Logan, R.W., Tianzhou, M., Lewis, D.A., Tseng, G.C., Sibille, E., and McClung, C.A. (2016) The effects of aging on circadian patterns of gene expression in the human prefrontal cortex. Proc Natl Acad Sci, USA, 113:206-11.
- Sidor, M.M., Spencer, S., Dzirasa, K., Parekh, P.K., Tye, K.M., Warden, M.R., Arey, R.N., Enwright III, J.F., Jacobsen, J.P.R., Kumar, S., Remillard, E.M., Caron, M.G., Deisseroth, K., and McClung, C.A. (2015) Daytime spikes in dopaminergic activity underlie rapid mood-cycling. Molecular Psychiatry, 20:1479-80.
- Ozburn, A.R., Falcon, E., Twaddle, A., Nugent, A.L., Gillman, A.G., Spencer, S.M., Arey, R.N., Mukherjee, S., Lyons-Weiler, J., Self, D.W., and McClung, C.A. (2014) Direct regulation of diurnal Drd3 expression and cocaine reward by NPAS2. Biological Psychiatry 77:425-33. *Selected as a priority communication.
- Arey, R., Enwright III, J.F., Spencer, S., Falcon, E., Ozburn, A.R., and McClung, C.A. (2013) An important role for Cholecystokinin, a CLOCK target gene, in the development and treatment of manic-like behaviors. Molecular Psychiatry, 19: 342-350.
The 5th Annual Sleep & Circadian Science Research Day Presents the Latest in Sleep and Circadian Science Research
Sleep researchers including Pitt Psychiatry faculty, trainees and students gathered in late November at the Pitt University Club to explore new research in the field of sleep and circadian science at the Center for Sleep and Circadian Science Research Day. Adriane Soehner, PhD (Assistant Professor of Psychiatry), chair of the organizing committee that included members across psychiatry, nursing, public health...
Now in Nature Communications: Diurnal Rhythms in Gene Expression in the Prefrontal Cortex in Schizophrenia
Researchers including Pitt Psychiatry investigators Marianne Seney, PhD, and Colleen McClung, PhD, have published a study in Nature Communications describing diurnal rhythms in gene expression in the dorsolateral prefrontal cortex in individuals with schizophrenia, compared with unaffected comparison subjects. Examining the postmortem brains of 46 comparison subjects and 46 subjects with schizophrenia...
Now in The Journal of Neuroscience: Circadian Protein NPAS2 Expression in the Nucleus Accumbens and Cocaine Reward
Disruptions of the circadian clock can contribute to or exacerbate vulnerability to substance use disorder in some populations. The laboratory of Dr. Colleen McClung (Professor of Psychiatry and Clinical and Translational Science) investigates the mechanisms by which circadian genes that regulate mood and impulsivity are involved in the risk for substance abuse. In a recent study published in the Journal of...
The Department of Psychiatry’s 19th Annual Research Day: A Day to Teach, Learn and Be Inspired
The 19th annual Department of Psychiatry Research Day on June 13, 2019 was our biggest yet! For the 505 faculty, postdoctoral students, residents, graduate students and staff who attended, the morning poster session and afternoon program offered a stimulating day of research and career development that was equal parts enlightenment, inspiration, fun and, at times, surprise. The morning session featured 140 posters...