Education & Training
Selected Honors & Awards
- Parekh, P.K., Becker-Krail, D., Sundaravelu, P., Ishigaki, S., Okado, H., Sobue, G., Huang, Y., and McClung, C.A. (2017) Altered GluA1 function and accumbal synaptic plasticity in the Clockdelta19 model of bipolar mania. Biological Psychiatry, in press
- Chen, C.Y., Logan, R.W., Tianzhou, M., Lewis, D.A., Tseng, G.C., Sibille, E., and McClung, C.A. (2016) The effects of aging on circadian patterns of gene expression in the human prefrontal cortex. Proc Natl Acad Sci, USA, 113:206-11.
- Sidor, M.M., Spencer, S., Dzirasa, K., Parekh, P.K., Tye, K.M., Warden, M.R., Arey, R.N., Enwright III, J.F., Jacobsen, J.P.R., Kumar, S., Remillard, E.M., Caron, M.G., Deisseroth, K., and McClung, C.A. (2015) Daytime spikes in dopaminergic activity underlie rapid mood-cycling. Molecular Psychiatry, 20:1479-80.
- Ozburn, A.R., Falcon, E., Twaddle, A., Nugent, A.L., Gillman, A.G., Spencer, S.M., Arey, R.N., Mukherjee, S., Lyons-Weiler, J., Self, D.W., and McClung, C.A. (2014) Direct regulation of diurnal Drd3 expression and cocaine reward by NPAS2. Biological Psychiatry 77:425-33. *Selected as a priority communication.
- Arey, R., Enwright III, J.F., Spencer, S., Falcon, E., Ozburn, A.R., and McClung, C.A. (2013) An important role for Cholecystokinin, a CLOCK target gene, in the development and treatment of manic-like behaviors. Molecular Psychiatry, 19: 342-350.
Colleen McClung, PhD Appointed Professor by Pitt School of Medicine
Colleen McClung, PhD is a pioneer in the study of how manipulations of limbic circuitry and circadian genes within this circuitry can lead to the development and treatment of psychiatric diseases. She combines molecular, cellular, physiological, and behavioral studies, incorporating new technologies, and these cutting-edge research activities have earned her a superb reputation in her field. Dr. McClung has...
Drs. Colleen A. McClung and Yanhua Huang Find That Nucleus Accumbens Excitatory Signaling Is Integral to Effects of Clock Gene Disruption on Manic-like Behaviors
Disruptions in circadian rhythms are associated with an increased risk for bipolar disorder, and the circadian protein CLOCK is involved in regulating monoaminergic systems and mood-related behavior. Colleen A. McClung, PhD , Professor of Psychiatry and Yanhua Huang, PhD , Assistant Professor of Psychiatry set out to clarify the molecular and synaptic mechanisms underlying this relationship. Working in...
Drs. Peter Franzen and Colleen McClung Receive NARSAD Independent Investigator Awards
The Department of Psychiatry is pleased to announce that two members of our faculty have been named the latest recipients of NARSAD Independent Investigator Awards by the Brain and Behavior Research Foundation. These two-year grants are awarded to researchers at the associate professor level and are designed to support a broad range of brain research projects. Colleen McClung, PhD Molecular Rhythms and Psychiatric...
The effects of aging on circadian patterns of gene expression in the human prefrontal cortex Chen C-Y, Logan RW, Ma T, Lewis DA, Tseng G, Sibille E and McClung CA Proceedings of the National Academy of Science, 2015, Published Online Examination of thousands of genes from nearly 150 human brains shows the circadian rhythm of gene activity changes with aging, according to a first-of-its-kind study conducted by...