Rui Peixoto, PhD

Assistant Professor of Psychiatry

Areas of Expertise

  • Basic & Translational Neuroscience
  • Neurodevelopmental Disorders
Rui Peixoto, PhD
Expertise & Interests Selected Publications Education & Credentials Related News

Expertise & Interests

Research Interests

Developmental neuroscience; Cortical and striatal development; Autism spectrum disorders

Education Interests

Research mentorship

Selected Publications

  1. Janecek M, Deemyad T, Shih Y-C, Valle V, D'Agostino A, Matarazzo M, Perez MS, Ketchesin KD, da Silva S, Peixoto RT (2025) Striatal output regulates the postnatal maturation of cortical circuits. Cell Reports 44(9):116187.
  2. Shih Y-C, Nelson L, Janecek M, Matarazzo M, D'Agostino A, Peixoto RT (2025) Early postnatal dysfunction of ACC PV interneurons in Shank3B KO mice. Molecular Psychiatry. doi:10.1038/s41380-025-03114-w.
  3. Peixoto RT, Chantranupong L, Hakim R, Levasseur J, Wang W, Merchant T, Gorman K, Budnik B, Sabatini BL (2019) Abnormal striatal development underlies the early onset of behavioral deficits in Shank3B KO mice. Cell Reports 29(7):2016-2027.e4.
  4. Peixoto RT, Wang W, Croney D, Kozorovitskiy Y, Sabatini BL (2016) Early hyperactivity and precocious maturation of corticostriatal circuits in Shank3B KO mice. Nature Neuroscience 19(5):716-24
  5. Peixoto RT, Kunz PA, Kwon H, Mabb AM, Sabatini BL, Philpot BD, Ehlers MD (2012) Trans-synaptic signaling by activity dependent cleavage of Neuroligin-1. Neuron 76(2):396-409.

Education & Credentials

Education & Training

Education
PhD, Neuroscience, Universidade Nova de Lisboa
Postdoctoral
Neurobiology, Harvard Medical School

Selected Honors & Awards

  • Young Investigator Award, Brain & Behavior Research Foundation
  • Bridge to Independence Award, Simons Foundation Autism Research Initiative (SFARI)

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