Mary L Phillips, MD

Pittsburgh Foundation-Emmerling Endowed Chair in Psychotic Disorders and Distinguished Professor of Psychiatry, Bioengineering, and Clinical and Translational Science

Current Appointments

  • Director, Center for Translational Research Incorporating Metabolism (CENTRIM-BD)
  • Director, Center for Neural-Circuit Based Technology Interventions in Psychiatry (CNCTI-P)

Areas of Expertise

  • Mood Disorders
  • Children & Adolescents
  • Basic & Translational Neuroscience
  • Neuromodulation
Mary L Phillips, MD

Expertise & Interests

Research Interests

Neuroimaging in mood disorders & OCD; Neuromodulation in mood disorders; Infant affective neural circuitry

Education Interests

Research mentoring

Selected Publications

  1. Aro Arora M, Chase H, Bertocci MA, Skeba AS, Eckstrand K, Bebko G, Aslam HA, Raeder R, Graur S, Benjamin O, Wang Y, Stiffler RS, Phillips ML. (2025). Left ventrolateral prefrontal cortical activity during reward expectancy and mania risk. JAMA Psychiatry. 2025 Mar 1;82(3):274-284. doi: 10.1001/jamapsychiatry.2024.4216. PMID: 39745759.
  2. Schumer MC, Bertocci MA, Aslam HA, Graur S, Bebko G, Stiffler RS, Skeba AS, Brady TJ, Benjamin OE, Wang Y, Chase HW, Phillips ML. Patterns of neural network functional connectivity associated with mania/hypomania and depression risk in 3 independent young adult samples. JAMA Psychiatry. 2024 Feb 1;81(2):167-177. doi: 10.1001/jamapsychiatry.2023.4150. PMID: 37910117.
  3. Ghane M, Trambaiolli L, Bertocci MA, Martinez-Rivera FJ, Chase HW, Brady T, Skeba A, Graur G, Bonar L, Iyengar S, Quirk GJ, RasmussenSA, Haber SN, Phillips ML. Specific patterns of endogenous functional connectivity are associated with harm avoidance in obsessive-compulsive disorder. Biol Psychiatry. 2024 Jul 15;96(2):137-146. doi: 10.1016/j.biopsych.2023.12.027. Epub 2024 Feb 8. PMID: 38336216.
  4. Afriyie-Agyemang Y, Bertocci Ma, Iyengar S, Stiffler RS, Bonar L, Aslam H, Graur S, Bebko B, Skeba A, Brady T, Benjamin O, Wang Y, Chase H, and Phillips ML. Lifetime depression and mania/hypomania risk predicted by neural markers in three independent young adult samples during working memory and emotional regulation. Mol Psychiatry. 2025 Mar;30(3):870-880. doi: 10.1038/s41380-024-02702-6. Epub 2024 Aug 29. PMID: 39210011.
  5. Zhang Y, Banihashemi L, Versace A, Samolyk A, Taylor M, English G, Schmithorst VJ, Lee VK, Stiffler R, Aslam H, Panigrahy A, Hipwell AE, Phillips ML. Early infant prefrontal cortical microstructure predicts present and future emotionality. Biol Psychiatry. 2024 Dec 15;96(12):959-970. doi: 10.1016/j.biopsych.2024.04.001. Epub 2024 Apr 9. PMID: 38604525; PMCID: PMC11461701.

Education & Credentials

Education & Training

Education
MD, Cambridge University
Residency
Psychiatry, Bethlem and Maudsley Hospitals Psychiatry Training

Professional Affiliations

  • President, Society of Biological Psychiatry
  • Council Member, Brain and Behavior Research Foundation
  • Member, American Psychiatric Association
  • Council Member, American College of Neuropsychopharmacology
  • Member, Society of Biological Psychiatry Women's Task Force

Selected Honors & Awards

  • Method to Extend Research in Time (MERIT) Award, National Institute of Mental Health
  • Highly Cited Researchers 2018 List, Clarivate Analytics
  • Chancellor's Distinguished Research Award, University of Pittsburgh
  • Colvin Prize for Bipolar Mood Disorder Research, Brain and Behavior Research Foundation
  • Joel Elkes Research Award, American College of Neuropsychopharmacology
  • Elected Member, American Society of Clinical Investigation