Marie Anne Gebara, MD

Associate Professor of Psychiatry

Current Appointments

  • Medical Director, Ketamine Services, Center for Interventional Psychiatry

Areas of Expertise

  • Older Adults
  • Neuromodulation
Marie Anne Gebara, MD
Expertise & Interests Selected Publications Education & Credentials Related News

Expertise & Interests

Research Interests

Treatment resistant depression; Sleep and mood disorders; Late-life depression

Clinical Interests

Long-term care; Treatment-resistant depression; Interventional psychiatry: Ketamine, ECT, and TMS

Education Interests

Interventional Psychiatry program development

Selected Publications

  1. Mak MSB, Gebara MA, Lenze EJ, Blumberger DM, Brown PJ, Cristancho P, Flint AJ, Karp JF, Lavretsky H, Miller JP, Reynolds CF 3rd, Roose SP, Mulsant BH, Stahl ST. Poor sleep is common in treatment-resistant late-life depression and associated with poorer antidepressant response: Findings From the OPTIMUM clinical trial. Am J Geriatr Psychiatry. 2025 Jan;33(1):63-72. doi: 10.1016/j.jagp.2024.07.020. Epub 2024 Aug 13. PMID: 39209616.
  2. Gebara MA, DiNapoli EA, Kasckow JW, Karp JF, Blumberger DM, Lenze EJ, Mulsant BH, Reynolds CF. Specific depressive symptoms predict remission to aripiprazole augmentation in late-life treatment resistant depression. Int J Geriatr Psychiatry. 2018; 33(2):e330-e335. PMCID: PMC5773368
  3. Gebara MA, Siripong N, DiNapoli EA, Maree RD, Germain A, Reynolds CF, Kasckow JW, Weiss PM, Karp JF. Effect of insomnia treatments on depression: A systematic review and meta-analysis. Depress Anxiety. 2018 Aug;35(8):717-731. doi: 10.1002/da.22776. Epub 2018 May 21. PMID: 29782076.
  4. Gebara MA, Lipsey KL, Karp JF, Nash MC, Iaboni A, Lenze EJ. Cause or effect? Selective serotonin reuptake inhibitors and falls in older adults: A systematic review. Am J Geriatr Psychiatry. 2015;23(10):1016-28
  5. Gebara MA, Shea ML, Lipsey KL, Teitelbaum SL, Civitelli R, Mller DJ, Reynolds CF 3rd, Mulsant BH, Lenze EJ. Depression, antidepressants, and bone health in older adults: A systematic review. J Am Geriatr Soc. 2014;62(8):1434-41.
  6. Lenze EJ, Mulsant BH, Roose SP, Lavretsky H, Reynolds CF 3rd, Blumberger DM, Brown PJ, Cristancho P, Flint AJ, Gebara MA, Gettinger TR, Lenard E, Miller JP, Nicol GE, Oughli HA, Pham VT, Rollman BL, Yang L, Karp JF. Antidepressant Augmentation versus Switch in Treatment-Resistant Geriatric Depression. N Engl J Med. 2023 Mar 23;388(12):1067-1079. doi: 10.1056/NEJMoa2204462. Epub 2023 Mar 3. PMID: 36867173; PMCID: PMC10568698.
  7. Oughli HA, Gebara MA, Ciarleglio A, Lavretsky H, Brown PJ, Flint AJ, Farber NB, Karp JF, Mulsant BH, Reynolds CF 3rd, Roose SP, Yang L, Butters MA, Lenze EJ. Intravenous Ketamine for Late-Life Treatment-Resistant Depression: A Pilot Study of Tolerability, Safety, Clinical Benefits, and Effect on Cognition. Am J Geriatr Psychiatry. 2023 Mar;31(3):210-221. doi: 10.1016/j.jagp.2022.11.013. Epub 2022 Dec 5. PMID: 36529623; PMCID: PMC10839705.
  8. Gebara MA, DiNapoli EA, Hamm ME, Rodrgiuez KL, Kaskow JW, Lederer LG, Bramoweth AD, Karp JF. Illness narratives and preferences for treatment among older veterans living with treatment resistant depression and insomnia. Annals of Clinical Psychiatry. 2020;32(2):81-89. PMID: 32343281
  9. Gebara MA, DiNapoli EA, Lederer LG, Bramoweth AD, Germain A, Kasckow JW, Karp JF. Brief behavioral treatment for insomnia in older adults with late-life treatment resistant depression and insomnia: A pilot study. Sleep and Biological Rhythms. 2019;17(3):287-295. PMCID: PMC6800686

Education & Credentials

Education & Training

Education
MD, American University of Beirut, Lebanon
Residency
Psychiatry, Barnes Jewish Hospital, St. Louis
Fellowship
Geriatric Psychiatry, UPMC Western Psychiatric Hospital
Postdoctoral
Clinical and Translational Research Training in Geriatric Psychiatry, University of Pittsburgh School of Medicine
Postdoctoral
Geriatric Psychiatry, VA Pittsburgh Healthcare System

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