Manivel L Rengasamy, MD

Assistant Professor of Psychiatry

Areas of Expertise

  • Children & Adolescents
  • Mood Disorders
  • Anxiety, OCD & Trauma Disorders

Expertise & Interests

Research Interests

Child & adolescent psychiatry; Neural substrates of suicidality & depression; Cytokines & inflammation

Clinical Interests

Child & adolescent psychiatry

Selected Publications

  1. Hossein S, Rengasamy M, Uzamere A, Spotts C, Howland RH, Wallace ML, Mathew SJ, Price RB. Effects of ketamine on individual symptoms and symptom networks of depression in a randomised controlled trial of ketamine for treatment-resistant depression. Br J Psychiatry. 2025 May 13:1-10. doi: 10.1192/bjp.2024.276. Epub ahead of print. PMID: 40355133; PMCID: PMC12310196.
  2. Rengasamy M, Mathew S, Howland R, Griffo A, Panny B, Price R. Neural connectivity moderators and mechanisms of ketamine treatment among treatment-resistant depressed patients: a randomized controlled trial. EBioMedicine. 2024 Jan;99:104902. doi: 10.1016/j.ebiom.2023.104902. Epub 2023 Dec 22. PMID: 38141395; PMCID: PMC10788398.
  3. Rengasamy M, Price R. Replicable and robust cellular and biochemical blood marker signatures of depression and depressive symptoms. Psychiatry Research. 2024 Dec 1;342:116190.
  4. Rengasamy M, Moriarity D, Kraynak T, Tervo-Clemmens B & Price R. (2023). Exploring the multiverse: the impact of researchers analytic decisions on relationships between depression and inflammatory markers. Neuropsychopharmacology, 48(10), 1465-1474.
  5. Rengasamy M, Sylvester C, Shulman J & Pizon A. (2020). Contemporary characteristics and lethality correlates of serious suicide attempts in children and adolescents. Suicide and Life-Threatening Behavior, 50(3), 714-723.
  6. Rengasamy M, Shalev A & Birmaher B. (2024). Psychopharmacology for Pediatric Depressive Disorders. In Pediatric Psychopharmacology Evidence: A Clinician's Guide (pp. 381-451). Cham: Springer Nature Switzerland.
  7. Rengasamy M & Birmaher B. Depressive Disorders. In Clinical manual of child and adolescent psychopharmacology. American Psychiatric Pub; 2023 Jul 28.
  8. Rengasamy M & Birmaher B. Bipolar II Disorder in Childhood and Adolescence. In Bipolar II Disorder: Recognition, Understanding, and Treatment. 2019 May 17 (pp. 241-262).
  9. Amin P, Esque J, Rengasamy M. Phone-Based Intervention for Suicidal Transition-Aged Adults, Poster presentation, UPMC Quality Improvement Fair. November 4, 2020.

Education & Credentials

Education & Training

Education
MD, University of Texas Health Science Center at Houston
Residency
Child & Adolescent Psychiatry, UPMC Western Psychiatric Hospital
Fellowship
Child & Adolescent Psychiatry, UPMC Western Psychiatric Hospital
Postdoctoral
Child & Adolescent Mental Health Research, University of Pittsburgh School of Medicine