Howard J Aizenstein, MD, PhD

Charles F. Reynolds III and Ellen G. Detlefsen Endowed Chair in Geriatric Psychiatry and Professor of Psychiatry, Bioengineering and Clinical and Translational Science

Current Appointments

  • Director, Clinical Research Training in Late-Life Mood Disorders
  • Director, Geriatric Psychiatry Neuroimaging Laboratory
  • Co-Director, Psychiatry Neuroimaging Program, Department of Psychiatry, University of Pittsburgh School of Medicine

Areas of Expertise

  • Older Adults
  • Mood Disorders
  • Anxiety, OCD & Trauma Disorders
Howard J Aizenstein, MD, PhD
Expertise & Interests Selected Publications Education & Credentials Related News

Expertise & Interests

Research Interests

Computational psychiatry; Geriatric mental health; Neuroimaging

Clinical Interests

Late-life depression; Dementia

Education Interests

Geriatric mental health research mentorship and tr; Mentoring in translational mental health research; Bioengineering in Psychiatry

Selected Publications

  1. Aizenstein H, Moore RC, Vahia I, Ciarleglio A. Deep Learning and Geriatric Mental Health. Am J Geriatr Psychiatry. 2024 Mar;32(3):270-279. Epub 2023 Dec 5. PMID: 38142162; PMCID: PMC10922602.
  2. Wu M, Thurston RC, Tudorascu DL, Karim HT, Mathis CA, Lopresti BJ, Kamboh MI, Cohen AD, Snitz BE, Klunk WE, Aizenstein HJ. Amyloid deposition is associated with different patterns of hippocampal connectivity in men versus women. Neurobiol Aging. 2019 Apr;76:141-150. Epub 2018 Dec 1. PMCID: PMC6584958.
  3. Lim HK, Nebes R, Snitz B, Cohen A, Mathis C, Price J, Weissfeld L, Klunk W, Aizenstein HJ. Regional amyloid burden and intrinsic connectivity networks in cognitively normal elderly subjects. Brain, 2014, 137(12):3327-38. PMCID: PMC4240287
  4. Aizenstein HJ, Andreescu C, Edelman KL, Cochran JL, Price J, Butters MA, Karp JF, Patel M, Reynolds CF 3rd. fMRI correlates of white matter hyperintensities in late-life depression. American Journal of Psychiatry, 2011, 168(10):1075-82. PMCID: PMC3656408
  5. Aizenstein HJ, Nebes RD, Saxton JA, Price JC, Mathis CA, Tsopelas ND, Ziolko SK, James JA, Snitz BE, Houck PR, Bi W, Cohen AD, Lopresti BJ, DeKosky ST, Halligan EM, Klunk WE. Frequent amyloid deposition without significant cognitive impairment among the elderly. Archives of Neurology, 2008, 65(11):1509-17. PMCID: PMC2636844

Education & Credentials

Education & Training

Education
MD, University of Illinois
Education
PhD, Computer Science, University of Illinois
Internship
General Psychiatry and Medicine, University of Pittsburgh School of Medicine
Residency
General and Adult Psychiatry, Western Psychiatric Institute and Clinic of UPMC
Fellowship
Geriatric Psychiatry, Western Psychiatric Institute and Clinic of UPMC
Postdoctoral
Geriatric Psychiatry, University of Pittsburgh School of Medicine

Professional Affiliations

  • Chair, Research Committee, American Association of Geriatric Psychiatry
  • Triage Editor, American Journal of Geriatric Psychiatry
  • Scientific Advisor, American Foundation for Suicide Prevention

Selected Honors & Awards

  • Pfizer-Eisai Alzheimer's Disease Research Award, American Association of Geriatric Psychiatry
  • Outstanding Mentorship Award, Western Psychiatric Institute and Clinic of UPMC

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