Guillermo R Gonzalez-Burgos, PhD

Associate Professor of Psychiatry

Areas of Expertise

  • Children & Adolescents
  • AI & Computational Methods
  • Psychosis
  • Basic & Translational Neuroscience
  • Anxiety, OCD & Trauma Disorders
Guillermo R Gonzalez-Burgos, PhD
Expertise & Interests Selected Publications Education & Credentials Related News

Expertise & Interests

Research Interests

Parvalbumin interneuron alterations; schizophrenia; Pyramidal neuron alterations in schizophrenia; Cellular basis of working memory & its alterations

Education Interests

Research mentorship

Selected Publications

  1. Joyce MKP, Ivanov TG, Krienen FM, Mitchell JF, Ma S, Inoue W, Nandy AS, Datta D, Duque A, Arellano JI, Gupta R, Gonzalez-Burgos G, Lewis DA, Sestan N, McCarroll SA, Martinez-Trujillo J, Froudist-Walsh S, Arnsten AFT. Higher dopamine D1 receptor expression in prefrontal parvalbumin neurons underlies higher distractibility in marmosets versus macaques. Commun Biol. 2025 Jul 1;8(1):974. doi: 10.1038/s42003-025-08297-0. PMID: 40594842; PMCID: PMC12214923.
  2. Koch NA, Corrigan BW, Feyerabend M, Gulli RA, Jimenez-Sosa MS, Abbass M, Sunstrum JK, Matovic S, Roussy M, Luna R, Mestern SA, Mahmoudian B, Vijayraghavan S, Igarashi H, Pradeepan KS, Assis WJ, Pruszynski JA, Tripathy S, Staiger JF, Gonzalez-Burgos G, Neef A, Treue S, Everling S, Inoue W, Khadra A, Martinez-Trujillo JC. Spike frequency adaptation in primate lateral prefrontal cortex neurons results from interplay between intrinsic properties and circuit dynamics. Cell Rep. 2025 Jan 28;44(1):115159. doi: 10.1016/j.celrep.2024.115159. Epub 2025 Jan 6. PMID: 39772396.
  3. Datta D, Yang S, Joyce MKP, Woo E, McCarroll SA, Gonzalez-Burgos G, Perone I, Uchendu S, Ling E, Goldman M, Berretta S, Murray J, Morozov Y, Arellano J, Duque A, Rakic P, O'Dell R, van Dyck CH, Lewis DA, Wang M, Krienen FM, Arnsten AFT. Key Roles of CACNA1C/Cav1.2 and CALB1/Calbindin in Prefrontal Neurons Altered in Cognitive Disorders. JAMA Psychiatry. 2024 Sep 1;81(9):870-881. doi: 10.1001/jamapsychiatry.2024.1112. PMID: 38776078; PMCID: PMC11112502.
  4. Rademacher J, Grent-'t-Jong T, Rivolta D, Sauer A, Scheller B, Gonzalez-Burgos G, Metzner C, Uhlhaas PJ. Computational modeling of ketamine-induced changes in gamma-band oscillations: The contribution of parvalbumin and somatostatin interneurons. PLoS Comput Biol. 2025 Jun 9;21(6):e1013118. doi: 10.1371/journal.pcbi.1013118. PMID: 40489551; PMCID: PMC12204622.
  5. Gonzalez Burgos G, Miyamae T, Nishihata Y, Krimer OL, Wade K, Fish KN, Arion D, Cai ZL, Xue M, Stauffer WR, Lewis DA. Synaptic alterations in pyramidal cells following genetic manipulation of neuronal excitability in monkey prefrontal cortex. bioRxiv [Preprint]. 2024 Jun 12:2024.06.12.598658. doi: 10.1101/2024.06.12.598658. Update in: J Neurophysiol. 2025 Feb 01;133(2):399-413. doi: 10.1152/jn.00326.2024. PMID: 38915638; PMCID: PMC11195287.

Education & Credentials

Education & Training

Education
PhD, Neuroscience, University of Buenos Aires, Argentina, School of Medicine
Postdoctoral
Neuroscience, University of Pittsburgh Kenneth P. Dietrich School of Arts and Sciences

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