Education & Training
Selected Honors & Awards
- KLUNK WE, Engler H, Nordberg A, Wang Y, Blomqvist G, Holt DP, Bergstrom M, Savitcheva I, Huang G-F, Estrada S, Ausen B, Debnath ML, Barletta J, Price JC, Sandell J, Lopresti BJ, Wall A, Koivisto P, Antoni G, Mathis CA and Langstrom,B. Imaging brain amyloid in Alzheimers disease with Pittsburgh Compound-B (PIB). Annals of Neurology 2004;55:306-319.
- Handen BL, Cohen AD, Channamalappa U, Bulova P, Cannon SA, Cohen WI, Mathis CA, Price JC and KLUNK WE. Imaging brain amyloid in nondemented young adults with Down syndrome using Pittsburgh compound B. Alzheimers &amp;amp; Dementia 2012;8:496-501.
- Lopez OL, KLUNK WE, Mathis C, Coleman RL, Price J, Becker JT, Aizenstein HJ, Snitz B, Cohen A, Ikonomovic M, McDade E, DeKosky ST, Weissfeld L and Kuller LH. Amyloid, neurodegeneration, and small vessel disease as predictors of dementia in the oldest-old. Neurology 2014;83:1804-1811.
- KLUNK WE, Koeppe RA, Price JC, Benzinger TL, Devous MD, Sr., Jagust WJ, Johnson KA, Mathis CA, Minhas D, Pontecorvo MJ, Rowe CC, Skovronsky DM and Mintun MA. The Centiloid Project: Standardizing quantitative amyloid plaque estimation by PET. Alzheimers Dement 2015;11:1-15.
- Yau WY, Tudorascu DL, McDade EM, Ikonomovic S, James JA, Minhas D, Mowrey W, Sheu LK, Snitz BE, Weissfeld L, Gianaros PJ, Aizenstein HJ, Price JC, Mathis CA, Lopez OL and KLUNK WE. Longitudinal assessment of neuroimaging and clinical markers in autosomal dominant Alzheimer's disease: a prospective cohort study. Lancet Neurol 2015;14:804-813.
Pitt Psychiatry Faculty Members Invited to Contribute to World Alzheimer Report
In fall 2021, Alzheimer’s Disease International published World Alzheimer Report 2021: Journey though the diagnosis of dementia, a compendium of research on the disease, currently the seventh leading cause of mortality worldwide. The report addresses numerous challenges and complexities—including the prevalence of myths and misinformation—that inhibit effective diagnosis and treatment Alzheimer’s disease. Pitt...
Dr. William Klunk Named UPMC Senior Services 2019 Grand Champion for Contributions to Alzheimer’s Research
We are proud to announce that William E. Klunk, MD, PhD (Distinguished Professor of Psychiatry and Neurology and Levidow-Pittsburgh Foundation Chair in Alzheimer's Disease and Dementia Disorders) and Chester Mathis, PhD (UPMC Endowed Chair of PET Research and Distinguished Professor of Radiology) have been honored as 2019 Grand Champions by UPMC Senior Services. This award is the highest honor given by UPMC Senior...
Publications by Department of Psychiatry Faculty Rank Among the Top 1% of Cited Works in 2018
Pictured above (left to right): Drs. William Klunk, David Lewis, Mary Phillips, Boris Birmaher, and Bernie Devlin The Department of Psychiatry is proud to announce that five current members of the faculty have been named Highly Cited Researchers for 2018: Boris Birmaher, MD; Bernie J. Devlin, PhD; William E. Klunk, MD, PhD; David A. Lewis, MD; and Mary L. Phillips, MD. Distinguished Emeritus Professor David J...
Accumulation of Amyloid Beta in Down Syndrome and Early-onset Alzheimer’s Follows a Different Path Than Late-onset Buildup
The brains of people with early-onset Alzheimer’s and Down syndrome share a distinct pattern of amyloid buildup that is not seen in late-onset Alzheimer’s disease. Future studies on the origin of this unique pattern could reveal important mechanisms of amyloid beta accumulation and possibly targets for early intervention. People with early-onset Alzheimer's disease often develop symptoms of cognitive decline in...