Lisa Pan, MD

Assistant Professor of Psychiatry, Clinical and Translational Science, Human Genetics and Obstetrics and Gynecology

Contact Details

3811 O'Hara St.
Anna Maria Segreti

Education & Training

Dartmouth University, Geisel School of Medicine Medicine
Western Psychiatric Institute and Clinic of UPMCPsychiatry and Child and Adolescent Psychiatry
Western Psychiatric Institute and Clinic of UPMCChild and Adolescent Psychiatry
University of Pittsburgh School of MedicineChild and Adolescent Psychiatry

Current Appointments

Director, Metabolomics of Treatment Refractory Depression and Early Suicide Attempt Programs
Medical Director, Shuman Juvenile Detention Center Mental Health Services

Professional Affiliations

Fellow, American Psychiatric Association
Member, American Academy of Child and Adolescent Psychiatry
Member, Society of Biological Psychiatry
Member, Society for Inherited Metabolic Disorders
Member, American Foundation for Suicide Prevention

Selected Honors & Awards

Pitt Innovation Challenge Award, University of Pittsburgh
NARSAD Young Investigator Award, Brain & Behavior Research Foundation
Young Investigator Award, American Foundation for Suicide Prevention

Research Interests

Metabolomics; Genomics; Neuroimaging
Selected Research Publications & Products
  1. Pan LA, Martin P, Zimmer T, Segreti AM, Kassiff S, McKain BW, Baca CA, Rengasamy M, Hyland K, Walano N, Steinfeld R, Hughes M, Dobrowolski SK, Pasquino M, Diler R, Perel J, Finegold DN, Peters DG, Naviaux RK, Brent DA, and Vockley G. Neurometabolic disorders: potentially treatable abnormalities in patients with treatment refractory depression and suicidal behavior. American Journal of Psychiatry. 2017; 174(1): 42-50.
  2. Pan, LA, Goldstein, TR, Rooks BT, Hickey M, Fan JY, Merranko J, Monk K, Diler RS, Sakolsky DJ, Hafeman, D, Iyengar S, Goldstein B, Kupfer DJ, Axelson D, Brent DA, Birmaher B. The Relationship Between Stressful Life Events and Axis I Diagnoses Among Adolescent Offspring of Probands With Bipolar and Non-Bipolar Psychiatric Disorders and Healthy Controls. 2017 Journal of Clinical Psychiatry. Mar;78(3):e234-e243.
  3. Pan L, Ramos L, Segreti A, Brent D, Phillips M. Abnormally diminished right superior temporal gyrus volume in adolescents with a history of suicide attempt. British Journal of Psychiatry. 2015; 206(4):339-40
  4. Pan, LA and ML Phillips. Toward identification of neural markers of suicide risk in adolescents. Neuropsychopharmacology Reviews. 2014; 39(1):236-7.
  5. Thomas LA and De Bellis MD. Pituitary volumes in pediatric maltreatment related PTSD. Biological Psychiatry 2004, 55(7):752-758.

Clinical Interests

Suicide prevention; Treatment refractory depression; Post-traumatic stress disorder
Selected Clinical Publications & Products
  1. Pan L and Vockley G. Neuropsychiatric Symptoms in Inborn Errors of Metabolism: Incorporation of Genomic and Metabolomic Analysis into Therapeutics and Prevention. Current Genetic Medicine Reports. 2013, 1:1, 65-70.
  2. Pan LA, McKain BW, Madan-Khetarpal S, McGuire M, Diler R, Perel JM, Vockley J, and Brent DA. GTP-Cyclohydrolase Deficiency Responsive to Sapropterin and 5HTP Supplementation: Relief of Treatment-Refractory Depression and Suicidal Behavior. BMJ Case Reports, 9 June 2011.
  3. Pan LA. Adolescent Suicidal Behavior. Oxford Handbook of Psychiatry. Kupfer D and Brent DA (eds.) Oxford Press, UK 2008.
  4. Pan LA. Adolescent Depressive Disorders. Oxford Handbook of Psychiatry. Kupfer D and Brent DA (eds.) Oxford Press, UK 2008.
  5. Pan LA and Brent DA. Child and adolescent depressive disorders. Current Diagnosis and Treatment in Psychiatry. Nurcombe B, Ebert M, and Leckman J (eds.) McGraw-Hill Lange, NY 2008.

Education Interests

Suicide prevention; Metabolomics; Neurobiology