Dana L Tudorascu, PhD

Associate Professor of Psychiatry and Biostatistics

Areas of Expertise

  • Anxiety, OCD & Trauma Disorders
  • Basic & Translational Neuroscience
Dana L Tudorascu, PhD
Expertise & Interests Selected Publications Education & Credentials Related News

Expertise & Interests

Research Interests

Neuroimaging studies of age-related pathology; Statistical methods for multimodal imaging studies; Alzheimer's disease

Selected Publications

  1. Chen CL, Son SJ, Schweitzer N, Jin H, Li J, Wang L, Yang S, Hong CH, Roh HW, Park B, Choi JW, An YS, Seo SW, Cho YH, Hong S, Nam YJ, Minhas DS, Laymon CM, Stetten GD, Tudorascu DL, Aizenstein HJ, Wu M; Mayo Clinic Study of Aging. Periventricular diffusivity reflects APOE e4-modulated amyloid accumulation and cognitive impairment in the Alzheimer's disease continuum. Alzheimers Dement. 2025 Sep;21(9):e70659. doi: 10.1002/alz.70659.PMID: 40965291
  2. Sjobeck GR, Torbati ME, Minhas DS, DeCarli CS, Wilson JD, Tudorascu DL. NetBat: A network-driven harmonization method for structural connectivity. Neuroimage. 2025 Aug 15;317:121317. doi: 10.1016/j.neuroimage.2025.121317. Epub 2025 Jun 23.PMID: 40562325.
  3. Chen CL, Torbati ME, Minhas DS, Laymon C, Hwang SJ, Bilgel M, Crainiceanu A, Luo W, Maillard P, Fletcher E, Crainiceanu CM, DeCarli C, Aizenstein HJ,Tudorascu DL. (2024). Superpixel-ComBat Modeling: A Joint Approach for Harmonization and Characterization of Inter-Scanner Variability in T1-Weighted Images. Imaging Neuroscience (2024) 2: imag-2-00306.
  4. Torbati ME, Minhas DS, Laymon CM, Maillard P, Wilson JD, Chen CL, Crainiceanu CM, DeCarli CS, Hwang SJ, Tudorascu DL. MISPEL: A supervised deep learning harmonization method for multi-scanner neuroimaging data, Med Image Anal 2023 Oct;89:102926.doi: 10.1016/j.media.2023.102926. Epub 2023 Aug 9, PMCID: PMC10529705
  5. Reynolds M, Chaudhary T, Torbati EM, Tudorascu DL, Batmanghelich K for the Alzheimer's Disease Neuroimaging Initiative. ComBat harmonization: Empirical Bayes versus fully Bayes approaches, NeuroImage Clinical, 2023, ISSN 2213-1582,https://doi.org/10.1016/j.nicl.2023.103472.
  6. Kennedy JT, Wisch JK, Dincer A, Roman J, Gordon BA, Handen B, Benzinger TLS, Head E, Mapstone M, Christian BT, Tudorascu DL, Laymon CL, Hartley SL, Lao P, Brickman AM, Zaman SH, Ances BM; ABC-DS and DIAN Consortia. Decoding brain structure to stage Alzheimer's disease pathology in Down syndrome. Alzheimers Dement. 2025 Feb;21(2):e14519. doi: 10.1002/alz.14519. Epub 2025 Jan 14.PMID: 3980762.
  7. Abdelmoity O, Wisch JK, Kennedy JT, Goyal M, Vlassenko A, Flores S, Handen BL, Head E, Keator D, Rafii MS, Lao P, Lai F, Rosas HD, Hartley SL, Zaman S, Brickman AM, Tudorascu D, Lee JH, Allegri RF, Keefe S, la Fougere C, Llibre-Guerra J, Ikeuchi T, Morris JC, Roh JH, Day GS, Levin J, Schofield PR, Gordon BA, Benzinger TLS, Ances BM; Alzheimer's Biomarker Consortium-Down Syndrome and the Dominantly Inherited Alzheimer Network. Cross-Sectional FDG in Down Syndrome and Autosomal Dominant Alzheimer's Disease. Ann Neurol. 2025 Sep 22. doi: 10.1002/ana.78002.
  8. Lao P, Edwards N, Flores-Aguilar L, Alshikho MJ, Smith A, LeMay R, Hahm J, Rizvi B, Tudorascu D, Rosas HD, Yassa M, Christian B, Mapstone M, Handen B; Alzheimer's Biomarkers ConsortiumDown Syndrome (ABC-DS) Investigators; Gutierrez J, Wilcock D, Head E, Brickman AM. Longitudinal changes in white matter hyperintensity volume accelerate across the Alzheimer's continuum in adults with Down syndrome. Alzheimers Dement. 2025 Sep;21(9):e70679. doi: 10.1002/alz.70679.PMID: 40951960
  9. Gogola A, Zeng X, Williams LA, Chapple-McGruder T, Saeed A, Lopresti BJ, Snitz B, Tudorascu D, Minhas D, Ikonomovic MD, Kofler J, Matan C, Pascoal TA, Aizenstein H, Zetterberg H, Blennow K, Lopez O, Villemagne VL, Karikari TK, Cohen AD. Impact of racialization on neuroimaging and plasma biomarkers of Alzheimer's disease. Alzheimers Dement. 2025 Jul;21(7):e70463. doi: 10.1002/alz.70463.PMID: 40631440
  10. Handen BL, Mapstone M, Hartley S, Andrews H, Christian B, Lee JH, Tudorascu D, Hom C, Ances BM, Zaman S, Krinsky-McHale S, Brickman AM, Rosas HD, Cohen A, Petersen M, O'Bryant S, Harp JP, Schmitt F, Ptomey L, Burns J, Lott IT, Lai F, Silverman W, Laymon C, Head E; Alzheimer's Biomarker Consortium Down Syndrome (ABC-DS). The Alzheimers Biomarkers Consortium: A 10-year report. Alzheimers Dement. 2025 May;21(5):e70294. doi: 10.1002/alz.70294.PMID: 40371686

Education & Credentials

Education & Training

Education
PhD, Biostatistics, University of Pittsburgh

Professional Affiliations

  • Member, American Statistical Association

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