Carmen Andreescu, MD

Professor of Psychiatry and Bioengineering

Current Appointments

  • Co-Director, Clinical Research Training in Late-Life Mood Disorders

Areas of Expertise

  • Older Adults
  • Mood Disorders
  • Anxiety, OCD & Trauma Disorders
  • Basic & Translational Neuroscience
  • Neuromodulation
Carmen Andreescu, MD

Expertise & Interests

Research Interests

Accelerated aging in late-life mood disorders; Neural basis of anxiety & depression in late-life; Biomarkers of treatment response

Clinical Interests

Late-life mood and anxiety disorders; Neurocognitive disorders; Brain stimulation therapies

Education Interests

Research mentorship; Resident education

Selected Publications

  1. Gerlach AR, Karim HT, Kolobaric A, Boyd BD, Kahru K, Krafty RT, Ajilore O, Taylor WD, Andreescu C. Network homeostasis: Functional brain network alterations and relapse in remitted late-life depression. Neuropsychopharmacology. 2025 May 29
  2. Kraynak TE, Karim HT, Banihashemi L, Krafty RT, Butters MA, Ajilore OA, Taylor WD, Andreescu C. Brain and cardiovascular responses to acute stress in remitted and recurrent late-life depression. Neuropsychopharmacology. 2025 May 50 (6): 956-964
  3. Wilson JD, Gerlach AR, Karim HT, Aizenstein HJ, Andreescu C. Sex matters: acute functional connectivity changes as markers of remission in late-life depression differ by sex. Mol Psychiatry. 2023 28(12):5228-5236
  4. Karim HT, Ly M, Yu G, Krafty R, Tudorascu DL, Aizenstein HJ, Andreescu C. Aging faster: Worry and rumination in late life are associated with greater brain age. Neurobiol Aging. 2021 May; 101:13-21
  5. Andreescu C, Lenze E, Lavretsky H. Is anxiety in late life an uncharted territory? Questioning the federal guidelines for anxiety screening in older adults. JAMA Psychiatry. 2023;80(3):197-198
  6. Andreescu C, Aijilore O, Aizenstein HJ, Albert K, Butters MA, Landman BA, Karim HT, Krafty R, Taylor WD. Disruption of neural homeostasis as a model of relapse and recurrence in late-life depression. Am J Geriatr Psychiatry. 2019 Dec 27; 27(12):1316-1330.
  7. Andreescu C, Varon D. New research on anxiety disorders in the elderly and an update on evidence-based treatments. Curr Psychiatry Rep. 2015
  8. Aizenstein HJ, Khalaf A, Walker SE, Andreescu C. Magnetic resonance imaging predictors of treatment response in late-life depression. J Geriatr Psychiatry Neurol. 2014
  9. Andreescu C, Aizenstein H. MRI studies in late-life mood disorders. Curr Top Behav Neurosci. 2012
  10. Varon D, Andreescu C: Amnestic Disorders and Mild Cognitive Impairment, in Kaplan & Sadocks Comprehensive Textbook of Psychiatry, 10th edition. Eds Benjamin J. Sadock, Virginia Alcott Sadock, Pedro Ruiz; Lippincott, Williams & Wilkins, Baltimore, 2016.
  11. Karim HT and Andreescu C. Anxiety disorders in older adults, in Kaplan & Sadocks Comprehensive Textbook of Psychiatry, 11th edition. Eds Benjamin J. Sadock, Virginia Alcott Sadock, Pedro Ruiz; Lippincott, Williams & Wilkins, Baltimore, MD, 2024
  12. Lenze EJ, Wetherell JL, Andreescu C: Anxiety disorders, in Essentials of Geriatric Psychiatry, 2nd edition. Eds Dan G. Blazer, David C. Steffens, American Psychiatric Publishing Press, Arlington VA, 2012
  13. Lenze EJ, Wetherell JL, Andreescu C: Anxiety disorders in the elderly, in American Psychiatric Association Textbook of Geriatric Neuropsychiatry, 3rd edition. American Psychiatric Publishing Inc., 2011
  14. Andreescu C, Aizenstein HJ: Amnestic disorders and mild cognitive impairment, in Kaplan & Sadocks Comprehensive Textbook of Psychiatry, 9th edition. Eds Benjamin J. Sadock, Virginia Alcott Sadock, Pedro Ruiz; Lippincott, Williams & Wilkins, Baltimore, 2010

Education & Credentials

Education & Training

Education
MD, Carol Davila University of Medicine and Pharmacy
Residency
Psychiatry, Western Psychiatric Institute and Clinic of UPMC
Fellowship
Geriatric Psychiatry, Western Psychiatric Institute and Clinic of UPMC

Professional Affiliations

  • Member, American Association for Geriatric Psychiatry

Selected Honors & Awards

  • Hartford-Jeste Award for Future Leaders in Geriatric Psychiatry, American Psychiatric Association
  • Young Investigator Award, Brain & Behavior Research Foundation