Events picture

Francis Lotrich, MD, PhD December 21, 2012, 12:00 pm - 1:30 pm WPIC Auditorium

Department of Psychiatry Lecture Series
Meet the PI Lecture


Cytokines and Depression: From Genes to Circuits to Targeted Treatments


Francis Lotrich, MD, PhD
Assistant Professor of Psychiatry
and Pharmaceutical Sciences
University of Pittsburgh

Dr. Lotrich earned his MD and a PhD in Behavioral Neuroscience from the Oregon Health & Science University.  He completed his residency training at Western Psychiatric Institute and Clinic where he served as Chief Resident, followed by postdoctoral training under the mentorship of Dr. Charles F. Reynolds, III.  Dr. Lotrich was appointed to the University of Pittsburgh Department of Psychiatry faculty in 2005.  His research interests focus on depression etiology, treatment, and prevention focusing on inflammatory cytokines, growth factors, and genetic vulnerability. As Director of the Biosignature Unit of the Late-Life Depression and Treatment Center, he is overseeing studies to examine cytokines, polymorphisms, and growth factors in elderly who are at risk for developing depression, overseeing ongoing prevention trials, and studying BDNF levels from prior treatment trials.  In addition to his numerous research projects, Dr. Lotrich is actively engaged in teaching and mentorship activities, and the provision of clinical services.

Learning Objectives:  Following this lecture, attendees will be able to:

  1. Recognize the link between interferon-alpha and depression.
  2. Discuss the potential role of genes and poor sleep in vulnerability to depression.
  3. Discuss potential treatments that might prevent inflammatory cytokine induced depression.

Continuing Education Credit: The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The University of Pittsburgh School of Medicine designates this educational activity for a maximum of 1.5 AMA PRA Category 1 Credits TM. Each physician should only claim credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded .15 continuing education units (CEUs), which are equal to 1.5 contact hours. In accordance with Accreditation Council for Continuing Medical Education requirements on disclosure, information about relationships of presenters with commercial interests (if any) will be included in materials which will be distributed at the time of the conference.  WPIC is approved by the American Psychological Association to offer continuing education for psychologists.  WPIC maintains responsibility for this program and its contents.  This program is being offered for 1.5 continuing education credits.

Please visit our web site at for more information on lectures and educational events sponsored by the Department of Psychiatry. 

For more information, please contact Jeanie Knox Houtsinger at